CHEBI:12256 - 7-hydroxyisoflavone

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ChEBI Name 7-hydroxyisoflavone
Definition The simplest member of the class of 7-hydroxyisoflavones that is isoflavone with a hydroxy substituent at position 7.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C15H10O3
Net Charge 0
Average Mass 238.23810
Monoisotopic Mass 238.06299
InChI InChI=1S/C15H10O3/c16-11-6-7-12-14(8-11)18-9-13(15(12)17)10-4-2-1-3-5-10/h1-9,16H
SMILES Oc1ccc2c(c1)occ(-c1ccccc1)c2=O
Roles Classification
Biological Role(s): EC (aromatase) inhibitor
An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC and so reduces production of estrogenic steroid hormones.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
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ChEBI Ontology
Outgoing 7-hydroxyisoflavone (CHEBI:12256) has role EC (aromatase) inhibitor (CHEBI:50790)
7-hydroxyisoflavone (CHEBI:12256) has role metabolite (CHEBI:25212)
7-hydroxyisoflavone (CHEBI:12256) is a 7-hydroxyisoflavones (CHEBI:55465)
7-hydroxyisoflavone (CHEBI:12256) is conjugate acid of 7-hydroxyisoflavone(1−) (CHEBI:77616)
Incoming 7-hydroxyisoflavone 7-O-β-D-glucoside (CHEBI:18174) has functional parent 7-hydroxyisoflavone (CHEBI:12256)
glycitein (CHEBI:34778) is a 7-hydroxyisoflavone (CHEBI:12256)
glycitein 4'-O-glucuronide (CHEBI:133667) is a 7-hydroxyisoflavone (CHEBI:12256)
7-hydroxyisoflavone(1−) (CHEBI:77616) is conjugate base of 7-hydroxyisoflavone (CHEBI:12256)
Synonym Source
4H-1-Benzopyran-4-one, 7-hydroxy-3-phenyl- ChemIDplus
Manual Xrefs Databases
EP0941992 Patent
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Registry Numbers Types Sources
13057-72-2 CAS Registry Number ChemIDplus
193534 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
16864424 PubMed citation Europe PMC
21562980 PubMed citation Europe PMC
22175340 PubMed citation Europe PMC
568259 Chinese Abstracts citation Europe PMC
Last Modified
21 February 2017