CHEBI:102516 - sulfamethoxypyridazine

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ChEBI Name sulfamethoxypyridazine
ChEBI ID CHEBI:102516
Definition A sulfonamide consisting of pyridazine having a methoxy substituent at the 6-position and a 4-aminobenzenesulfonamido group at the 3-position.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C11H12N4O3S
Net Charge 0
Average Mass 280.304
Monoisotopic Mass 280.063
InChI InChI=1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
InChIKey VLYWMPOKSSWJAL-UHFFFAOYSA-N
SMILES C1=CC(=CC=C1N)S(NC2=NN=C(C=C2)OC)(=O)=O
Roles Classification
Biological Role(s): EC 2.5.1.15 (dihydropteroate synthase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via sulfonamide antibiotic )
Application(s): antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing sulfamethoxypyridazine (CHEBI:102516) has functional parent sulfanilamide (CHEBI:45373)
sulfamethoxypyridazine (CHEBI:102516) has role antiinfective agent (CHEBI:35441)
sulfamethoxypyridazine (CHEBI:102516) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502)
sulfamethoxypyridazine (CHEBI:102516) is a pyridazines (CHEBI:37921)
sulfamethoxypyridazine (CHEBI:102516) is a sulfonamide (CHEBI:35358)
sulfamethoxypyridazine (CHEBI:102516) is a sulfonamide antibiotic (CHEBI:87228)
IUPAC Name
4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
INNs Sources
sulfamethoxypyridazine KEGG DRUG
sulfamethoxypyridazinum ChemIDplus
sulfametoxipiridazina ChemIDplus
Synonyms Sources
3-(4-Aminobenzenesulfonamido)-6-methoxypyridazine NIST Chemistry WebBook
3-(p-Aminobenzenesulfamido)-6-methoxypyridazine ChemIDplus
3-Methoxy-6-sulfanylamidopyridazine ChemIDplus
3-p-Aminobenzenesulphonamido-6-methoxypyridazine ChemIDplus
3-Sulfa-6-methoxypyridazine ChemIDplus
3-Sulfanilamide-6-methoxypyridazine ChemIDplus
3-Sulfanilamido-6-methoxypyridazine ChemIDplus
4-Amino-N-(6-methoxy-3-pyridazinyl)-benzenesulfonamide NIST Chemistry WebBook
6-Methoxy-3-pyridazinylsulfanilamide NIST Chemistry WebBook
6-Methoxy-3-sulfanilamidopyridazine ChemIDplus
6-Sulfanilamido-3-methoxypyridazine ChemIDplus
N1-(6-Methoxy-3-pyridazinyl)sulfanilamide NIST Chemistry WebBook
Solfametossipiridazina ChemIDplus
sulfamethoxipyridazine ChEBI
Sulfametoxipiridazine ChemIDplus
Sulphamethoxypyridazine ChemIDplus
Manual Xrefs Databases
2515 DrugCentral
D02439 KEGG DRUG
LSM-5204 LINCS
US2712012 Patent
View more database links
Registry Numbers Types Sources
1443440 Gmelin Registry Number Gmelin
277076 Reaxys Registry Number Reaxys
277076 Beilstein Registry Number Beilstein
80-35-3 CAS Registry Number KEGG DRUG
80-35-3 CAS Registry Number ChemIDplus
80-35-3 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
11431418 PubMed citation Europe PMC
13363378 PubMed citation Europe PMC
13488278 PubMed citation Europe PMC
13521763 PubMed citation Europe PMC
13559967 PubMed citation Europe PMC
13583950 PubMed citation Europe PMC
13615757 PubMed citation Europe PMC
13635077 PubMed citation Europe PMC
23183348 PubMed citation Europe PMC
6864729 PubMed citation ChEMBL
7486915 PubMed citation Europe PMC
Last Modified
22 February 2017