CHEBI:100922 - SB 505124

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ChEBI Name SB 505124
ChEBI ID CHEBI:100922
Definition A member of the class of imidazoles carrying tert-butyl, 1,3-benzodioxol-5-yl and 6-methylpyridin-2-yl substituents at positions 2, 4 and 5 respectively.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C20H21N3O2
Net Charge 0
Average Mass 335.400
Monoisotopic Mass 335.163
InChI InChI=1S/C20H21N3O2/c1-12-6-5-7-14(21-12)18-17(22-19(23-18)20(2,3)4)13-8-9-15-16(10-13)25-11-24-15/h5-10H,11H2,1-4H3,(H,22,23)
InChIKey WGZOTBUYUFBEPZ-UHFFFAOYSA-N
SMILES N1=C(C=CC=C1C=2NC(=NC2C3=CC=4OCOC4C=C3)C(C)(C)C)C
Roles Classification
Biological Role(s): TGFbeta receptor antagonist
An antagonist that binds to and deactivates TGFbeta receptors.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing SB 505124 (CHEBI:100922) has role TGFβ receptor antagonist (CHEBI:91202)
SB 505124 (CHEBI:100922) is a benzodioxole (CHEBI:38733)
SB 505124 (CHEBI:100922) is a imidazoles (CHEBI:24780)
SB 505124 (CHEBI:100922) is a methylpyridines (CHEBI:25340)
IUPAC Name
2-[4-(2H-1,3-benzodioxol-5-yl)-2-tert-butyl-1H-imidazol-5-yl]-6-methylpyridine
Synonyms Sources
2-[4-(1,3-benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridin ChEBI
SB-505124 ChEBI
SB505124 ChEBI
Registry Number Type Source
11751238 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
26343586 PubMed citation Europe PMC
26363490 PubMed citation Europe PMC
26427712 PubMed citation Europe PMC
26531758 PubMed citation Europe PMC
26586478 PubMed citation Europe PMC
26984936 PubMed citation Europe PMC
Last Modified
08 July 2016