CHEBI:90914 - uridine triacetate

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ChEBI Name uridine triacetate
Definition An acetate ester that is uracil in which the three hydroxy hydrogens are replaced by acetate group. A prodrug for uridine, it is used for the treatment of hereditary orotic aciduria and for management of fluorouracil toxicity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C15H18N2O9
Net Charge 0
Average Mass 370.312
Monoisotopic Mass 370.10123
InChI InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1
SMILES [C@@H]1(N2C(NC(=O)C=C2)=O)O[C@H](COC(=O)C)[C@H]([C@H]1OC(=O)C)OC(=O)C
Roles Classification
Application(s): prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
orphan drug
Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease.
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ChEBI Ontology
Outgoing uridine triacetate (CHEBI:90914) has role neuroprotective agent (CHEBI:63726)
uridine triacetate (CHEBI:90914) has role orphan drug (CHEBI:71031)
uridine triacetate (CHEBI:90914) has role prodrug (CHEBI:50266)
uridine triacetate (CHEBI:90914) is a acetate ester (CHEBI:47622)
uridine triacetate (CHEBI:90914) is a uridines (CHEBI:27242)
INN Source
uridine triacetate KEGG DRUG
Synonyms Sources
2',3',5'-Triacetyluridine ChemIDplus
PN 401 ChemIDplus
PN401 ChemIDplus
RG 2133 ChemIDplus
Tri-O-acetyluridine ChemIDplus
Triacetyluridine ChemIDplus
Uridine 2',3',5'-triacetate ChemIDplus
Brand Name Source
Manual Xref Database
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Registry Numbers Types Sources
4105-38-8 CAS Registry Number KEGG COMPOUND
4105-38-8 CAS Registry Number ChemIDplus
97869 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
14642447 PubMed citation Europe PMC
16187114 PubMed citation Europe PMC
16330000 PubMed citation Europe PMC
17011205 PubMed citation Europe PMC
21930638 PubMed citation Europe PMC
23648515 PubMed citation Europe PMC
26535019 PubMed citation Europe PMC
Last Modified
22 February 2017