CHEBI:87715 - prasugrel

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ChEBI Name prasugrel
ChEBI ID CHEBI:87715
Definition A racemate comprising equal amounts of (R)- and (S)-prasugrel. Used (as its hydrochloride salt) to prevent blood clots in people with acute coronary syndrome who are undergoing a procedure after a recent heart attack or stroke, and in people with certain disorders of the heart or blood vessels.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C20H20FNO3S
Net Charge 0
Average Mass 373.443
Roles Classification
Biological Role(s): platelet glycoprotein-IIb/IIIa receptor antagonist
Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
P2Y12 receptor antagonist
An antagonist at the P2Y12 receptor
Application(s): platelet glycoprotein-IIb/IIIa receptor antagonist
Antagonist of platelet surface glycoprotein-IIb/IIIa which has a key role in hemostasis and thrombosis such as platelet adhesion and aggregation.
cardiovascular drug
A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
prodrug
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing prasugrel (CHEBI:87715) has part (R)-prasugrel (CHEBI:87725)
prasugrel (CHEBI:87715) has part (S)-prasugrel (CHEBI:87724)
prasugrel (CHEBI:87715) has role cardiovascular drug (CHEBI:35554)
prasugrel (CHEBI:87715) has role P2Y12 receptor antagonist (CHEBI:68563)
prasugrel (CHEBI:87715) has role platelet glycoprotein-IIb/IIIa receptor antagonist (CHEBI:50433)
prasugrel (CHEBI:87715) has role prodrug (CHEBI:50266)
prasugrel (CHEBI:87715) is a racemate (CHEBI:60911)
IUPAC Name
rac-5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
INN Source
prasugrel ChemIDplus
Synonyms Sources
(±)-prasugrel ChEBI
(RS)-prasugrel ChEBI
CS 747 ChemIDplus
CS-747 ChemIDplus
HSDB 7995 ChemIDplus
LY 640315 ChemIDplus
LY-640315 ChemIDplus
LY640315 ChemIDplus
rac-prasugrel ChEBI
racemic prasugrel ChEBI
Manual Xrefs Databases
DB06209 DrugBank
HMDB0015625 HMDB
Prasugrel Wikipedia
View more database links
Registry Numbers Types Sources
150322-43-3 CAS Registry Number ChemIDplus
9008623 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017