CHEBI:8768 - rabeprazole

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ChEBI Name rabeprazole
ChEBI ID CHEBI:8768
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C18H21N3O3S
Net Charge 0
Average Mass 359.44300
Monoisotopic Mass 359.130
InChI InChI=1S/C18H21N3O3S/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21)
InChIKey YREYEVIYCVEVJK-UHFFFAOYSA-N
SMILES COCCCOc1ccnc(CS(=O)c2nc3ccccc3[nH]2)c1C
Roles Classification
Biological Role(s): EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H+/K+-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors.
Application(s): anti-ulcer drug
One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
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ChEBI Ontology
Outgoing rabeprazole (CHEBI:8768) has role anti-ulcer drug (CHEBI:49201)
rabeprazole (CHEBI:8768) has role EC 3.6.3.10 (H+/K+-exchanging ATPase) inhibitor (CHEBI:49200)
rabeprazole (CHEBI:8768) is a benzimidazoles (CHEBI:22715)
rabeprazole (CHEBI:8768) is a pyridines (CHEBI:26421)
rabeprazole (CHEBI:8768) is a sulfoxide (CHEBI:22063)
rabeprazole (CHEBI:8768) is conjugate acid of rabeprazole(1−) (CHEBI:49199)
Incoming rabeprazole(1−) (CHEBI:49199) is conjugate base of rabeprazole (CHEBI:8768)
IUPAC Name
2-({[4-(3-methoxypropoxy)-3-methylpyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole
INN Source
rabeprazole ChEBI
Synonyms Sources
Clofezone ChemIDplus
Rabeprazole KEGG COMPOUND
Manual Xrefs Databases
2350 DrugCentral
C07864 KEGG COMPOUND
D08463 KEGG DRUG
DB01129 DrugBank
LSM-5045 LINCS
Rabeprazole Wikipedia
View more database links
Registry Numbers Types Sources
117976-89-3 CAS Registry Number KEGG COMPOUND
117976-89-3 CAS Registry Number ChemIDplus
8159014 Beilstein Registry Number Beilstein
Last Modified
22 February 2017