CHEBI:78698 - dafachronic acids

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ChEBI Name dafachronic acids
Definition Any of a family of steroid acids derived from sterols by oxidation with a cytochrome p450 that bind and activate the orphan nuclear receptor DAF-12 in the nematode Caenorhabditis elegans. Note that the singular term 'dafachronic acid' has been used as a synonym for the (non-natural) fully saturated (5α,25S)-3-oxocholestan-26-oic acid.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dafachronic acids (CHEBI:78698) is a 3-oxo steroid (CHEBI:47788)
dafachronic acids (CHEBI:78698) is a cholestanoid (CHEBI:50401)
dafachronic acids (CHEBI:78698) is a monocarboxylic acid (CHEBI:25384)
dafachronic acids (CHEBI:78698) is a steroid acid (CHEBI:47891)
dafachronic acids (CHEBI:78698) is a steroid hormone (CHEBI:26764)
Incoming Δ17-dafachronic acid (CHEBI:83137) is a dafachronic acids (CHEBI:78698)
Δ4-dafachronic acid (CHEBI:78686) is a dafachronic acids (CHEBI:78698)
Δ7-dafachronic acid (CHEBI:78699) is a dafachronic acids (CHEBI:78698)
(5α)-3-oxocholestan-26-oic acid (CHEBI:78701) is a dafachronic acids (CHEBI:78698)
Citations Waiting for Citations Types Sources
16529801 PubMed citation Europe PMC
19005586 PubMed citation Europe PMC
20135027 PubMed citation Europe PMC
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Last Modified
24 September 2014