CHEBI:7859 - oxycodone hydrochloride

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ChEBI Name oxycodone hydrochloride
ChEBI ID CHEBI:7859
Definition A hydrochloride obtained by reaction of oxycodone with one molar equivalent of hydrochloric acid. It is a moderately potent opioid analgesic, generally used for relief of moderate to severe pain.
Stars This entity has been manually annotated by the ChEBI Team.
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Formulae C18H21NO4.HCl
C18H22ClNO4
Net Charge 0
Average Mass 351.825
Monoisotopic Mass 351.124
InChI InChI=1S/C18H21NO4.ClH/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10;/h3-4,13,16,21H,5-9H2,1-2H3;1H/t13-,16+,17+,18-;/m1./s1
InChIKey MUZQPDBAOYKNLO-RKXJKUSZSA-N
SMILES C=12[C@@]34[C@@]5([C@H](N(C)CC3)CC1C=CC(=C2O[C@H]4C(=O)CC5)OC)O.Cl
Roles Classification
Biological Role(s): mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
Application(s): mu-opioid receptor agonist
A compound that exhibits agonist activity at the mu-opioid receptor.
antitussive
An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
opioid analgesic
A narcotic or opioid substance, synthetic or semisynthetic agent producing profound analgesia, drowsiness, and changes in mood.
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ChEBI Ontology
Outgoing oxycodone hydrochloride (CHEBI:7859) has part oxycodone(1+) (CHEBI:134686)
oxycodone hydrochloride (CHEBI:7859) has role μ-opioid receptor agonist (CHEBI:55322)
oxycodone hydrochloride (CHEBI:7859) has role antitussive (CHEBI:51177)
oxycodone hydrochloride (CHEBI:7859) has role opioid analgesic (CHEBI:35482)
oxycodone hydrochloride (CHEBI:7859) is a hydrochloride (CHEBI:36807)
Incoming Troxyca ER (CHEBI:134679) has part oxycodone hydrochloride (CHEBI:7859)
IUPAC Names
(5α,17S)-14-hydroxy-3-methoxy-17-methyl-6-oxo-4,5-epoxymorphinan-17-ium chloride
14-hydroxy-3-methoxy-17-methyl-4,5α-epoxymorphinan-6-one hydrochloride
Synonyms Sources
14-Hydroxydihydrocodeinone hydrochloride ChemIDplus
4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one hydrochloride ChemIDplus
Dihydrone hydrochloride ChemIDplus
Dihydrooxycodeinone hydrochloride ChemIDplus
Dihydroxycodeinone hydrochloride ChemIDplus
Oxycodone HCl ChemIDplus
Oxycodone hydrochloride KEGG COMPOUND
oxycodone monohydrochloride ChEBI
Manual Xrefs Databases
C08026 KEGG COMPOUND
D00847 KEGG DRUG
DB00497 DrugBank
Oxycodone Wikipedia
View more database links
Registry Numbers Types Sources
124-90-3 CAS Registry Number ChemIDplus
3782141 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
27780305 PubMed citation Europe PMC
Last Modified
22 February 2017