CHEBI:77319 - oltipraz

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ChEBI Name oltipraz
Definition A 1,2-dithiole that is 3H-1,2-dithiole-3-thione substituted at positions 4 and 5 by methyl and pyrazin-2-yl groups respectively.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C8H6N2S3
Net Charge 0
Average Mass 226.34200
Monoisotopic Mass 225.96931
InChI InChI=1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
SMILES Cc1c(ssc1=S)-c1cnccn1
Roles Classification
Chemical Role(s): antioxidant
A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides.
Biological Role(s): antimutagen
An agent that reduces or interferes with the mutagenic actions or effects of a substance.
EC (protein-tyrosine-phosphatase) inhibitor
An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins.
A poison that interferes with the functions of the nervous system.
Application(s): angiogenesis modulating agent
An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
protective agent
Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent.
schistosomicide drug
Drugs that used to treat infestations by flukes (trematodes) of the genus Schistosoma.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing oltipraz (CHEBI:77319) has role angiogenesis modulating agent (CHEBI:50926)
oltipraz (CHEBI:77319) has role antimutagen (CHEBI:73190)
oltipraz (CHEBI:77319) has role antineoplastic agent (CHEBI:35610)
oltipraz (CHEBI:77319) has role antioxidant (CHEBI:22586)
oltipraz (CHEBI:77319) has role EC (protein-tyrosine-phosphatase) inhibitor (CHEBI:35608)
oltipraz (CHEBI:77319) has role neurotoxin (CHEBI:50910)
oltipraz (CHEBI:77319) has role protective agent (CHEBI:50267)
oltipraz (CHEBI:77319) has role schistosomicide drug (CHEBI:38941)
oltipraz (CHEBI:77319) is a 1,2-dithiole (CHEBI:48859)
oltipraz (CHEBI:77319) is a pyrazines (CHEBI:38314)
INNs Sources
oltipraz ChemIDplus
oltipraz WHO MedNet
oltipraz WHO MedNet
oltiprazum ChemIDplus
Synonyms Sources
4-Methyl-5-pyrazinyl-3H-1,2-dithiole-3-thione ChemIDplus
5-(2-Pyrazinyl)-4-methyl-1,2-dithiole-3-thione ChemIDplus
RP 35972 ChemIDplus
RP-35,972 ChemIDplus
Manual Xrefs Databases
HMDB0041967 HMDB
Oltipraz Wikipedia
View more database links
Registry Numbers Types Sources
64224-21-1 CAS Registry Number ChemIDplus
978110 Beilstein Registry Number ChemIDplus
978110 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
07 March 2014