CHEBI:76591 - (25R)-cholest-5-ene-3β,26-diol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name (25R)-cholest-5-ene-3β,26-diol
ChEBI ASCII Name (25R)-cholest-5-ene-3beta,26-diol
Definition A 26-hydroxycholesterol in which the 25-position has R-configuration.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter KAX
Supplier Information
Download Molfile XML SDF
Formula C27H46O2
Net Charge 0
Average Mass 402.65290
Monoisotopic Mass 402.34978
InChI InChI=1S/C27H46O2/c1-18(17-28)6-5-7-19(2)23-10-11-24-22-9-8-20-16-21(29)12-14-26(20,3)25(22)13-15-27(23,24)4/h8,18-19,21-25,28-29H,5-7,9-17H2,1-4H3/t18-,19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
SMILES C[C@@H](CO)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Roles Classification
Biological Role(s): apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
(via 26-hydroxycholesterol )
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
EC (carboxylesterase) inhibitor
Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC ).
(via 26-hydroxycholesterol )
Application(s): neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (25R)-cholest-5-ene-3β,26-diol (CHEBI:76591) has functional parent cholesterol (CHEBI:16113)
(25R)-cholest-5-ene-3β,26-diol (CHEBI:76591) has role apoptosis inducer (CHEBI:68495)
(25R)-cholest-5-ene-3β,26-diol (CHEBI:76591) has role human metabolite (CHEBI:77746)
(25R)-cholest-5-ene-3β,26-diol (CHEBI:76591) has role mouse metabolite (CHEBI:75771)
(25R)-cholest-5-ene-3β,26-diol (CHEBI:76591) has role neuroprotective agent (CHEBI:63726)
(25R)-cholest-5-ene-3β,26-diol (CHEBI:76591) is a 26-hydroxycholesterol (CHEBI:17703)
Incoming (25R)-3β-hydroxycholest-5-en-26-al (CHEBI:86096) has functional parent (25R)-cholest-5-ene-3β,26-diol (CHEBI:76591)
Synonyms Sources
(25R)-26-hydroxycholesterol ChEBI
(25R)-cholest-5-ene-3β,26-diol ChEBI
(25R)-Cholest-5-ene-3beta,26-diol ChemIDplus
(25R)-cholest-5-ene-3β,26-diol UniProt
27-Hydroxycholesterol ChemIDplus
5-cholestene-3beta,27-diol ChemIDplus
Cholest-5-ene-3beta,27-diol ChemIDplus
Registry Numbers Types Sources
20380-11-4 CAS Registry Number ChemIDplus
3161261 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
21546230 PubMed citation Europe PMC
22281802 PubMed citation Europe PMC
22652365 PubMed citation Europe PMC
22884615 PubMed citation Europe PMC
23041327 PubMed citation Europe PMC
23111110 PubMed citation Europe PMC
23168292 PubMed citation Europe PMC
23246833 PubMed citation Europe PMC
23850851 PubMed citation Europe PMC
23951005 PubMed citation Europe PMC
24210818 PubMed citation Europe PMC
24269812 PubMed citation Europe PMC
24288332 PubMed citation Europe PMC
24370436 PubMed citation Europe PMC
Last Modified
25 April 2017