CHEBI:76310 - (±)-menthol

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ChEBI Name (±)-menthol
ChEBI ASCII Name (+-)-menthol
Definition A racemate comprising equimolar amounts of (+)- and (−)-menthol. Both (±)- and (−)-menthol are used to relieve symptoms of conditions such as bronchitis and sinusitis. When applied to the skin, menthol dilates the blood vessels, giving a sensation of coldness followed by an analgesic effect that relieves itching. It is therefore used in creams and ointments for the relief of pruritis and urticaria.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Application(s): antipruritic drug
A drug, usually applied topically, that relieves pruritus (itching).
vasodilator agent
A drug used to cause dilation of the blood vessels.
An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (±)-menthol (CHEBI:76310) has part (−)-menthol (CHEBI:15409)
(±)-menthol (CHEBI:76310) has part (+)-menthol (CHEBI:76306)
(±)-menthol (CHEBI:76310) has role antipruritic drug (CHEBI:59683)
(±)-menthol (CHEBI:76310) has role antispasmodic drug (CHEBI:53784)
(±)-menthol (CHEBI:76310) has role antitussive (CHEBI:51177)
(±)-menthol (CHEBI:76310) has role vasodilator agent (CHEBI:35620)
(±)-menthol (CHEBI:76310) is a racemate (CHEBI:60911)
INNs Sources
racémenthol WHO MedNet
racementhol ChemIDplus
racementholum ChemIDplus
racementol ChemIDplus
Synonyms Sources
(+/-)-menthol ChEBI
d,l-menthol ChemIDplus
dl-menthol KEGG DRUG
DL-menthol ChEBI
rac-menthol ChemIDplus
Manual Xref Database
View more database links
Registry Numbers Types Sources
89-78-1 CAS Registry Number KEGG DRUG
89-78-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12806393 PubMed citation Europe PMC
18640200 PubMed citation Europe PMC
IND20570977 Agricola citation Europe PMC
Last Modified
19 November 2013