CHEBI:66338 - UCS1025 A

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ChEBI Name UCS1025 A
ChEBI ID CHEBI:66338
Definition An organic heterotricyclic compound that incorporates a lactam and a γ-lactone as part of the cyclic system which in turn is attached to a (2,4a,8a-trimethyl-octahydronaphthalen-1-yl)carbonyl group at position 7. It is isolated from Acremonium sp. KY4917 and exhibits antibacterial activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C22H29NO5
Net Charge 0
Average Mass 387.46940
Monoisotopic Mass 387.20457
InChI InChI=1S/C22H29NO5/c1-12-6-10-20(2)8-4-5-9-21(20,3)15(12)16(24)14-17-22(27)13(19(26)28-17)7-11-23(22)18(14)25/h6,10,12-15,17,27H,4-5,7-9,11H2,1-3H3/t12-,13-,14-,15+,17-,20+,21+,22+/m0/s1
InChIKey WOAILDKFDXKSIY-OMKDVXPQSA-N
SMILES [H][C@]12CCN3C(=O)[C@@]([H])(C(=O)[C@H]4[C@@H](C)C=C[C@@]5(C)CCCC[C@]45C)[C@]([H])(OC1=O)[C@]23O
Metabolite of Species Details
Acremonium (NCBI:txidtxid5045) of strain KY4917 See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing UCS1025 A (CHEBI:66338) has role antibacterial agent (CHEBI:33282)
UCS1025 A (CHEBI:66338) has role antimicrobial agent (CHEBI:33281)
UCS1025 A (CHEBI:66338) has role antineoplastic agent (CHEBI:35610)
UCS1025 A (CHEBI:66338) has role metabolite (CHEBI:25212)
UCS1025 A (CHEBI:66338) is a γ-lactone (CHEBI:37581)
UCS1025 A (CHEBI:66338) is a ketone (CHEBI:17087)
UCS1025 A (CHEBI:66338) is a lactam (CHEBI:24995)
UCS1025 A (CHEBI:66338) is a octahydronaphthalenes (CHEBI:138397)
UCS1025 A (CHEBI:66338) is a organic heterotricyclic compound (CHEBI:26979)
UCS1025 A (CHEBI:66338) is a tertiary alcohol (CHEBI:26878)
IUPAC Name
(2aR,7R,7aS,7bR)-7b-hydroxy-7-{[(1S,2S,4aR,8aR)-2,4a,8a-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]carbonyl}hexahydrofuro[2,3,4-gh]pyrrolizine-2,6-dione
Manual Xrefs Databases
EP1227097 Patent
US6869971 Patent
WO0129043 Patent
View more database links
Citations Waiting for Citations Types Sources
10819301 PubMed citation Europe PMC
12465894 PubMed citation Europe PMC
16402826 PubMed citation Europe PMC
16492035 PubMed citation Europe PMC
Last Modified
07 September 2017