CHEBI:65763 - 5,5'-dibutoxy-2,2'-bifuran

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ChEBI Name 5,5'-dibutoxy-2,2'-bifuran
Definition A ring assembly that consists of 2,2'-bifuran substituted by butoxy groups at positions 5 and 5' respectively. It is isolated from the aerial parts of Chrysanthemum coronarium and acts as an inhibitor of human AcylCoA:cholesterol acyltransferase hACAT-1 and hACAT-2.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C16H22O4
Net Charge 0
Average Mass 278.34350
Monoisotopic Mass 278.152
InChI InChI=1S/C16H22O4/c1-3-5-11-17-15-9-7-13(19-15)14-8-10-16(20-14)18-12-6-4-2/h7-10H,3-6,11-12H2,1-2H3
SMILES CCCCOc1ccc(o1)-c1ccc(OCCCC)o1
Metabolite of Species Details
Chrysanthemum coronarium (NCBI:txid99038) Found in aerial part (BTO:0001658). See: PubMed
Roles Classification
Biological Role(s): EC (sterol O-acyltransferase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of acyl-CoA:cholesterol acyltransferase (EC
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) has role EC (sterol O-acyltransferase) inhibitor (CHEBI:64696)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) has role metabolite (CHEBI:25212)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) is a ether (CHEBI:25698)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) is a furans (CHEBI:24129)
5,5'-dibutoxy-2,2'-bifuran (CHEBI:65763) is a ring assembly (CHEBI:36820)
Registry Number Type Source
20775042 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
18481011 PubMed citation Europe PMC
Last Modified
04 January 2013