CHEBI:65638 - CJ-01

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ChEBI Name CJ-01
ChEBI ID CHEBI:65638
Definition A sesquiterpenoid that is 4,4a,7,8,8a,9-hexahydronaphtho[2,3-b]furan substituted by methyl groups at positions 3, 5 and 8a and an oxo group at position 9 (the 4aS,8aS stereoisomer). It is isolated from the methanol extract of the whole plant of Chloranthus japonicus and acts as a chitin synthase inhibitor. CJ-01 also shows antifungal activity against various human and phytophathogenic fungi.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C15H18O2
Net Charge 0
Average Mass 230.30220
Monoisotopic Mass 230.13068
InChI InChI=1S/C15H18O2/c1-9-5-4-6-15(3)12(9)7-11-10(2)8-17-13(11)14(15)16/h5,8,12H,4,6-7H2,1-3H3/t12-,15-/m0/s1
InChIKey PJUXIGJXLKHONL-WFASDCNBSA-N
SMILES [H][C@@]12Cc3c(C)coc3C(=O)[C@@]1(C)CCC=C2C
Metabolite of Species Details
Chloranthus japonicus (NCBI:txidtxid13007) Found in whole plant (BTO:0001461). See: PubMed
Roles Classification
Biological Role(s): EC 2.4.1.16 (chitin synthase) inhibitor
A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16).
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing CJ-01 (CHEBI:65638) has role antifungal agent (CHEBI:35718)
CJ-01 (CHEBI:65638) has role EC 2.4.1.16 (chitin synthase) inhibitor (CHEBI:59672)
CJ-01 (CHEBI:65638) has role metabolite (CHEBI:25212)
CJ-01 (CHEBI:65638) is a aromatic ketone (CHEBI:76224)
CJ-01 (CHEBI:65638) is a cyclic ether (CHEBI:37407)
CJ-01 (CHEBI:65638) is a cyclic terpene ketone (CHEBI:36130)
CJ-01 (CHEBI:65638) is a enone (CHEBI:51689)
CJ-01 (CHEBI:65638) is a organic heterotricyclic compound (CHEBI:26979)
CJ-01 (CHEBI:65638) is a sesquiterpenoid (CHEBI:26658)
IUPAC Name
(4aS,8aS)-3,5,8a-trimethyl-4a,7,8,8a-tetrahydronaphtho[2,3-b]furan-9(4H)-one
Citation Waiting for Citations Type Source
18451544 PubMed citation Europe PMC
Last Modified
07 November 2013