CHEBI:65538 - cadiyenol

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ChEBI Name cadiyenol
Definition An acetylenic compound that is (8E)-heptadeca-1,8-diene-4,6-diyne substituted by hydroxy group at positions 6 and 15, a methoxy group at position 8 and a (5-methoxy-5-oxopentyl)oxy group at position 7. Isolated from Centella asiatica, it exhibits antineoplastic activity.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C24H36O6
Net Charge 0
Average Mass 420.53900
Monoisotopic Mass 420.25119
InChI InChI=1S/C24H36O6/c1-5-7-10-16-21(26)24(30-19-14-13-18-23(27)29-4)22(28-3)17-12-9-8-11-15-20(25)6-2/h6,12,17,20-22,24-26H,2,5,7,10,13-14,16,18-19H2,1,3-4H3/b17-12+
Metabolite of Species Details
Centella asiatica (NCBI:txid48106) Found in aerial part (BTO:0001658). See: PubMed
Roles Classification
Biological Role(s): apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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ChEBI Ontology
Outgoing cadiyenol (CHEBI:65538) has role antineoplastic agent (CHEBI:35610)
cadiyenol (CHEBI:65538) has role apoptosis inducer (CHEBI:68495)
cadiyenol (CHEBI:65538) has role metabolite (CHEBI:25212)
cadiyenol (CHEBI:65538) is a acetylenic compound (CHEBI:73474)
cadiyenol (CHEBI:65538) is a diether (CHEBI:46786)
cadiyenol (CHEBI:65538) is a diol (CHEBI:23824)
cadiyenol (CHEBI:65538) is a methyl ester (CHEBI:25248)
cadiyenol (CHEBI:65538) is a secondary alcohol (CHEBI:35681)
methyl 5-{[(9E)-6,15-dihydroxy-8-methoxyheptadeca-9,16-diene-11,13-diyn-7-yl]oxy}pentanoate
Registry Number Type Source
11222769 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
17520525 PubMed citation Europe PMC
Last Modified
11 March 2015