CHEBI:65349 - mirabegron

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ChEBI Name mirabegron
Definition A monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2-amino-1,3-thiazol-4-ylacetic acid with the anilino group of (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol. Used for the treatment of overactive bladder syndrome.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C21H24N4O2S
Net Charge 0
Average Mass 396.50600
Monoisotopic Mass 396.16200
InChI InChI=1S/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)/t19-/m0/s1
SMILES Nc1nc(CC(=O)Nc2ccc(CCNC[C@H](O)c3ccccc3)cc2)cs1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
Application(s): beta-adrenergic agonist
An agent that selectively binds to and activates beta-adrenergic receptors.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing mirabegron (CHEBI:65349) has role β-adrenergic agonist (CHEBI:35522)
mirabegron (CHEBI:65349) is a 1,3-thiazoles (CHEBI:38418)
mirabegron (CHEBI:65349) is a aromatic amide (CHEBI:62733)
mirabegron (CHEBI:65349) is a ethanolamines (CHEBI:23981)
mirabegron (CHEBI:65349) is a monocarboxylic acid amide (CHEBI:29347)
INN Source
mirabegron ChemIDplus
Brand Name Source
Myrbetriq ChEBI
Manual Xrefs Databases
4382 DrugCentral
EP1559427 Patent
EP2119700 Patent
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Registry Numbers Types Sources
11023250 Reaxys Registry Number Reaxys
223673-61-8 CAS Registry Number KEGG DRUG
223673-61-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
20878594 PubMed citation Europe PMC
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Last Modified
22 February 2017