CHEBI:59120 - thioproperazine

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ChEBI Name thioproperazine
Definition A phenothiazine derivative in which the phenothiazine tricycle has a dimethylaminosulfonyl substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at N-10.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C22H30N4O2S2
Net Charge 0
Average Mass 446.62900
Monoisotopic Mass 446.18102
InChI InChI=1S/C22H30N4O2S2/c1-23(2)30(27,28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3
SMILES CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)S(=O)(=O)N(C)C)CC1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Application(s): phenothiazine antipsychotic drug

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ChEBI Ontology
Outgoing thioproperazine (CHEBI:59120) has role phenothiazine antipsychotic drug (CHEBI:37930)
thioproperazine (CHEBI:59120) is a N-alkylpiperazine (CHEBI:46845)
thioproperazine (CHEBI:59120) is a N-methylpiperazine (CHEBI:46920)
thioproperazine (CHEBI:59120) is a phenothiazines (CHEBI:38093)
thioproperazine (CHEBI:59120) is a sulfonamide (CHEBI:35358)
INNs Sources
thioproperazine KEGG DRUG
thioproperazinum DrugBank
tioproferazina DrugBank
Synonyms Sources
(Thioproperazine)-2-dimethylsulfamido-(10-(3-1-methylpiperazinyl-4)propyl)-phenothiazine ChemIDplus
2-dimethylsulfamido-(10-(3-1-methylpiperazinyl-4)propyl)-phenothiazine NIST Chemistry WebBook
N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine-2-sulfonamide NIST Chemistry WebBook
N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide NIST Chemistry WebBook
Thioperazine DrugBank
Thioproperazin DrugBank
Tioproperazina ChemIDplus
Manual Xrefs Databases
2635 DrugCentral
DB01622 DrugBank
GB814512 Patent
HMDB0015559 HMDB
Thioproperazine Wikipedia
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Registry Numbers Types Sources
316-81-4 CAS Registry Number ChemIDplus
316-81-4 CAS Registry Number NIST Chemistry WebBook
633101 Beilstein Registry Number Beilstein
633101 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
14137303 PubMed citation Europe PMC
14190465 PubMed citation Europe PMC
14201648 PubMed citation Europe PMC
1650428 PubMed citation Europe PMC
35804 PubMed citation Europe PMC
6120723 PubMed citation Europe PMC
Last Modified
22 February 2017