CHEBI:145520 - Fasnall

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name Fasnall
Definition A racemate comprising equimolar amounts of (R)- and (S)-Fasnall. Both enantiomers act as fatty acid synthase inhibitors, although the (S)-enantiomer was found to be more than 4 times as active as the (R)-enantiomer.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Ceri
Supplier Information
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Formula C19H22N4S
Net Charge 0
Average Mass 338.470
Monoisotopic Mass 338.15652
InChI InChI=1S/C19H22N4S/c1-13-14(2)24-19-17(13)18(20-12-21-19)22-16-8-9-23(11-16)10-15-6-4-3-5-7-15/h3-7,12,16H,8-11H2,1-2H3,(H,20,21,22)
Roles Classification
Biological Role(s): EC (fatty acid synthase) inhibitor
An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC, a multi-enzyme protein involved in fatty acid synthesis.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
anti-HIV agent
An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
fatty acid synthesis inhibitor
Any pathway inhibitor that inhibits the synthesis of fatty acids.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing Fasnall (CHEBI:145520) has part (R)-Fasnall (CHEBI:145533)
Fasnall (CHEBI:145520) has part (S)-Fasnall (CHEBI:145534)
Fasnall (CHEBI:145520) has role anti-HIV agent (CHEBI:64946)
Fasnall (CHEBI:145520) has role apoptosis inducer (CHEBI:68495)
Fasnall (CHEBI:145520) has role EC (fatty acid synthase) inhibitor (CHEBI:71476)
Fasnall (CHEBI:145520) has role fatty acid synthesis inhibitor (CHEBI:50185)
Fasnall (CHEBI:145520) is a racemate (CHEBI:60911)
Registry Number Type Source
929978-58-5 CAS Registry Number ChEBI
Citations Waiting for Citations Types Sources
27265747 PubMed citation SUBMITTER
28962653 PubMed citation Europe PMC
29177652 PubMed citation Europe PMC
31769890 PubMed citation Europe PMC
Last Modified
27 November 2019