CHEBI:134504 - tenofovir(1−)

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ChEBI Name tenofovir(1−)
ChEBI ASCII Name tenofovir(1-)
Definition A phosphorus oxoanion resulting from the removal of one proton from the phosphonic acid group of tenofovir. The major microspecies at pH 7.3.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anne Morgat
Supplier Information
Download Molfile XML SDF
Formula C9H13N5O4P
Net Charge -1
Average Mass 286.205
Monoisotopic Mass 286.07106
InChI InChI=1S/C9H14N5O4P/c1-6(18-5-19(15,16)17)2-14-4-13-7-8(10)11-3-12-9(7)14/h3-4,6H,2,5H2,1H3,(H2,10,11,12)(H2,15,16,17)/p-1/t6-/m1/s1
SMILES N1(C=2C(=C(N)N=CN2)N=C1)C[C@H](OCP(O)(=O)[O-])C
Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
HIV-1 reverse transcriptase inhibitor
An entity which inhibits the activity of HIV-1 reverse transcriptase.
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tenofovir(1−) (CHEBI:134504) has role antiviral drug (CHEBI:36044)
tenofovir(1−) (CHEBI:134504) has role HIV-1 reverse transcriptase inhibitor (CHEBI:53756)
tenofovir(1−) (CHEBI:134504) is a phosphorus oxoanion (CHEBI:33461)
tenofovir(1−) (CHEBI:134504) is conjugate base of tenofovir (anhydrous) (CHEBI:63625)
Incoming tenofovir (anhydrous) (CHEBI:63625) is conjugate acid of tenofovir(1−) (CHEBI:134504)
hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
Synonyms Sources
tenofovir UniProt
tenofovir (1−) ChEBI
Citation Waiting for Citations Type Source
15914676 PubMed citation SUBMITTER
Last Modified
12 April 2017