CHEBI:133246 - tetramethylpyrazine

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ChEBI Name tetramethylpyrazine
Definition A member of the class of pyrazines that is pyrazine in which all four hydrogens have been replaced by methyl groups. An alkaloid extracted from Chuanxiong (Ligusticum wallichii).
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Sabrina Toro
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Formula C8H12N2
Net Charge 0
Average Mass 136.195
Monoisotopic Mass 136.10005
InChI InChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
Metabolite of Species Details
Ligusticum wallichii (IPNI: 844646-1) See: PubMed
Corynebacterium glutamicum (NCBI:txid1718) See: European Journal of Organic Chemistry, 2010 , 2687-2695
Ephedra sinica (NCBI:txid33152) See: PubMed
Roles Classification
Biological Role(s): apoptosis inhibitor
Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms.
bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
neuroprotective agent
Any compound that can be used for the treatment of neurodegenerative disorders.
vasodilator agent
A drug used to cause dilation of the blood vessels.
platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
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ChEBI Ontology
Outgoing tetramethylpyrazine (CHEBI:133246) has role antineoplastic agent (CHEBI:35610)
tetramethylpyrazine (CHEBI:133246) has role apoptosis inhibitor (CHEBI:68494)
tetramethylpyrazine (CHEBI:133246) has role bacterial metabolite (CHEBI:76969)
tetramethylpyrazine (CHEBI:133246) has role neuroprotective agent (CHEBI:63726)
tetramethylpyrazine (CHEBI:133246) has role platelet aggregation inhibitor (CHEBI:50427)
tetramethylpyrazine (CHEBI:133246) has role vasodilator agent (CHEBI:35620)
tetramethylpyrazine (CHEBI:133246) is a alkaloid (CHEBI:22315)
tetramethylpyrazine (CHEBI:133246) is a pyrazines (CHEBI:38314)
Synonyms Sources
2,3,5,6,-tetramethyl-1,4-pyrazine MetaCyc
2,3,5,6-tetramethylpyrazine ChemIDplus
FEMA No. 3237 ChemIDplus
liqustrazine ChemIDplus
Manual Xrefs Databases
CPD-15901 MetaCyc
HMDB0036584 HMDB
Tetramethylpyrazine Wikipedia
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Registry Numbers Types Sources
1124-11-4 CAS Registry Number ChemIDplus
1124-11-4 CAS Registry Number NIST Chemistry WebBook
113100 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
02 October 2018