CHEBI:131532 - pyridoxamine dihydrochloride

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ChEBI Name pyridoxamine dihydrochloride
ChEBI ID CHEBI:131532
Definition A hydrochloride obtained by combining pyridoxamine with two molar equivalents of hydrochloric acid. Used for treatment of diabetic nephropathy.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C8H14Cl2N2O2
Net Charge 0
Average Mass 241.115
Monoisotopic Mass 240.04323
InChI InChI=1S/C8H12N2O2.2ClH/c1-5-8(12)7(2-9)6(4-11)3-10-5;;/h3,11-12H,2,4,9H2,1H3;2*1H
InChIKey HNWCOANXZNKMLR-UHFFFAOYSA-N
SMILES C1(O)=C(C)N=CC(CO)=C1CN.Cl.Cl
Metabolite of Species Details
Mus musculus (NCBI:txid10090) See: PubMed
Escherichia coli (NCBI:txid562) See: PubMed
Homo sapiens (NCBI:txid9606) See: DOI
Roles Classification
Chemical Role(s): iron chelator

Biological Role(s): mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
Application(s): nephroprotective agent
Any protective agent that is able to prevent damage to the kidney.
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ChEBI Ontology
Outgoing pyridoxamine dihydrochloride (CHEBI:131532) has part pyridoxamine(2+) (CHEBI:131533)
pyridoxamine dihydrochloride (CHEBI:131532) has role Escherichia coli metabolite (CHEBI:76971)
pyridoxamine dihydrochloride (CHEBI:131532) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
pyridoxamine dihydrochloride (CHEBI:131532) has role human metabolite (CHEBI:77746)
pyridoxamine dihydrochloride (CHEBI:131532) has role iron chelator (CHEBI:38157)
pyridoxamine dihydrochloride (CHEBI:131532) has role mouse metabolite (CHEBI:75771)
pyridoxamine dihydrochloride (CHEBI:131532) has role nephroprotective agent (CHEBI:76595)
pyridoxamine dihydrochloride (CHEBI:131532) has role plant metabolite (CHEBI:76924)
pyridoxamine dihydrochloride (CHEBI:131532) is a hydrochloride (CHEBI:36807)
IUPAC Names
4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol dihydrochloride
4-(azaniumylmethyl)-3-hydroxy-5-(hydroxymethyl)-2-methylpyridin-1-ium dichloride
Synonyms Sources
2-Methyl-3-hydroxy-4-aminomethyl-5-hydroxymethylpyridene dihydrochloride ChemIDplus
4-(Aminomethyl)-5-hydroxy-6-methyl-3-pyridinemethanol dihydrochloride ChemIDplus
Pyridoxamine dichlorohydrate ChemIDplus
Pyridoxylamine dihydrochloride ChemIDplus
Manual Xref Database
Pyridoxamine Wikipedia
View more database links
Registry Numbers Types Sources
3632748 Reaxys Registry Number Reaxys
524-36-7 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
25532068 PubMed citation Europe PMC
Last Modified
15 March 2016