CHEBI:131351 - CGS 15943

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name CGS 15943
Definition A member of the class of triazoloquinazolines that is [1,2,4]triazolo[1,5-c]quinazoline substited at positions 2, 5 and 9 by furan-2-yl, amino and chloro groups respectively. A potent antagonist at adenosine A1 and adenosine A2A receptors.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C13H8ClN5O
Net Charge 0
Average Mass 285.689
Monoisotopic Mass 285.04174
InChI InChI=1S/C13H8ClN5O/c14-7-3-4-9-8(6-7)12-17-11(10-2-1-5-20-10)18-19(12)13(15)16-9/h1-6H,(H2,15,16)
SMILES N=1C2=C(C=3N(C1N)N=C(N3)C=4OC=CC4)C=C(C=C2)Cl
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): adenosine A1 receptor antagonist
An antagonist at the A1 receptor.
adenosine A2A receptor antagonist
An antagonist at the A2A receptor.
Application(s): central nervous system stimulant
Any drug that enhances the activity of the central nervous system.
antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing CGS 15943 (CHEBI:131351) has role adenosine A1 receptor antagonist (CHEBI:63957)
CGS 15943 (CHEBI:131351) has role adenosine A2A receptor antagonist (CHEBI:53121)
CGS 15943 (CHEBI:131351) has role antineoplastic agent (CHEBI:35610)
CGS 15943 (CHEBI:131351) has role central nervous system stimulant (CHEBI:35337)
CGS 15943 (CHEBI:131351) is a aromatic amine (CHEBI:33860)
CGS 15943 (CHEBI:131351) is a biaryl (CHEBI:64459)
CGS 15943 (CHEBI:131351) is a furans (CHEBI:24129)
CGS 15943 (CHEBI:131351) is a organochlorine compound (CHEBI:36683)
CGS 15943 (CHEBI:131351) is a primary amino compound (CHEBI:50994)
CGS 15943 (CHEBI:131351) is a triazoloquinazoline (CHEBI:131355)
Synonyms Sources
9-Chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine ChemIDplus
CGS 15943A ChemIDplus
CGS-15943 ChEBI
CGS15943 ChEBI
Manual Xref Database
CGS-15943 Wikipedia
View more database links
Registry Numbers Types Sources
104615-18-1 CAS Registry Number ChemIDplus
4237267 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
10440083 PubMed citation Europe PMC
1888997 PubMed citation Europe PMC
1943461 PubMed citation Europe PMC
1953988 PubMed citation Europe PMC
1987452 PubMed citation Europe PMC
24521981 PubMed citation Europe PMC
2883298 PubMed citation Europe PMC
7689104 PubMed citation Europe PMC
7723470 PubMed citation Europe PMC
8007757 PubMed citation Europe PMC
8229772 PubMed citation Europe PMC
8627553 PubMed citation Europe PMC
8760180 PubMed citation Europe PMC
9933143 PubMed citation Europe PMC
Last Modified
29 February 2016