CHEBI:8354 - pralidoxime

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ChEBI Name pralidoxime
ChEBI ID CHEBI:8354
Definition A pyridinium ion that is 1-methylpyridinium substituted by a (hydroxyimino)methyl group at position 2.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C7H9N2O
Net Charge +1
Average Mass 137.15924
Monoisotopic Mass 137.071
InChI InChI=1S/C7H8N2O/c1-9-5-3-2-4-7(9)6-8-10/h2-6H,1H3/p+1
InChIKey JBKPUQTUERUYQE-UHFFFAOYSA-O
SMILES C[n+]1ccccc1\C=N\O
Roles Classification
Biological Role(s): cholinergic drug
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
cholinesterase reactivator
A drug used to reverse the inactivation of cholinesterase caused by organophosphates or sulfonates.
Application(s): cholinergic drug
Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons.
antidote to organophosphate poisoning
A role borne by a molecule that acts to counteract or neutralise the deleterious effects of organophosphates or acetylcholinesterase inhibitors (nerve agents).
antidote to sarin poisoning
A role borne by a molecule that acts to counteract or neutralise the nerve agent sarin.
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ChEBI Ontology
Outgoing pralidoxime (CHEBI:8354) has role antidote to organophosphate poisoning (CHEBI:90753)
pralidoxime (CHEBI:8354) has role antidote to sarin poisoning (CHEBI:136860)
pralidoxime (CHEBI:8354) has role cholinergic drug (CHEBI:38323)
pralidoxime (CHEBI:8354) has role cholinesterase reactivator (CHEBI:50241)
pralidoxime (CHEBI:8354) is a pyridinium ion (CHEBI:50334)
Incoming pralidoxime chloride (CHEBI:8355) has part pralidoxime (CHEBI:8354)
pralidoxime iodide (CHEBI:32038) has part pralidoxime (CHEBI:8354)
pralidoxime mesylate (CHEBI:50240) has part pralidoxime (CHEBI:8354)
IUPAC Name
2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium
INN Source
pralidoxime ChemIDplus
Synonyms Sources
Pralidoxime KEGG COMPOUND
Pralidoximum ChemIDplus
Manual Xrefs Databases
2231 DrugCentral
C07400 KEGG COMPOUND
DB00733 DrugBank
HMDB0014871 HMDB
LSM-5708 LINCS
Pralidoxime Wikipedia
View more database links
Registry Numbers Types Sources
1526531 Reaxys Registry Number Reaxys
1526531 Beilstein Registry Number Beilstein
6735-59-7 CAS Registry Number KEGG COMPOUND
6735-59-7 CAS Registry Number ChemIDplus
Citation Waiting for Citations Type Source
24625936 PubMed citation Europe PMC
Last Modified
20 April 2017