CHEBI:8058 - phencyclidine

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ChEBI Name phencyclidine
Definition A member of the class of piperidines that is piperidine in which the nitrogen is substituted with a 1-phenylcyclohexyl group. Formerly used as an anaesthetic agent, it exhibits both hallucinogenic and neurotoxic effects.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C17H25N
Net Charge 0
Average Mass 243.38710
Monoisotopic Mass 243.19870
InChI InChI=1S/C17H25N/c1-4-10-16(11-5-1)17(12-6-2-7-13-17)18-14-8-3-9-15-18/h1,4-5,10-11H,2-3,6-9,12-15H2
Roles Classification
Biological Role(s): NMDA receptor antagonist
Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs.
A poison that interferes with the functions of the nervous system.
Application(s): psychotropic drug
A loosely defined grouping of drugs that have effects on psychological function.
Substance which produces loss of feeling or sensation.
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ChEBI Ontology
Outgoing phencyclidine (CHEBI:8058) has parent hydride piperidine (CHEBI:18049)
phencyclidine (CHEBI:8058) has role anaesthetic (CHEBI:38867)
phencyclidine (CHEBI:8058) has role neurotoxin (CHEBI:50910)
phencyclidine (CHEBI:8058) has role NMDA receptor antagonist (CHEBI:60643)
phencyclidine (CHEBI:8058) has role psychotropic drug (CHEBI:35471)
phencyclidine (CHEBI:8058) is a benzenes (CHEBI:22712)
phencyclidine (CHEBI:8058) is a piperidines (CHEBI:26151)
INNs Sources
fenciclidina ChemIDplus
phencyclidine ChemIDplus
phencyclidinum ChemIDplus
Synonyms Sources
PCP ChemIDplus
Phencyclidine KEGG COMPOUND
Manual Xrefs Databases
1PC PDBeChem
2121 DrugCentral
DB03575 DrugBank
Phencyclidine Wikipedia
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Registry Numbers Types Sources
20976544 Reaxys Registry Number Reaxys
77-10-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017