CHEBI:78741 - oxidopamine

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ChEBI Name oxidopamine
Definition A benzenetriol that is phenethylamine in which the hydrogens at positions 2, 4, and 5 on the phenyl ring are replaced by hydroxy groups. It occurs naturally in human urine, but is also produced as a metabolite of the drug DOPA (used for the treatment of Parkinson's disease).
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C8H11NO3
Net Charge 0
Average Mass 169.17780
Monoisotopic Mass 169.074
InChI InChI=1S/C8H11NO3/c9-2-1-5-3-7(11)8(12)4-6(5)10/h3-4,10-12H,1-2,9H2
SMILES NCCc1cc(O)c(O)cc1O
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): neurotoxin
A poison that interferes with the functions of the nervous system.
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
drug metabolite

molecular messenger

(via monoamine molecular messenger )
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ChEBI Ontology
Outgoing oxidopamine (CHEBI:78741) has functional parent dopamine (CHEBI:18243)
oxidopamine (CHEBI:78741) has role drug metabolite (CHEBI:49103)
oxidopamine (CHEBI:78741) has role human metabolite (CHEBI:77746)
oxidopamine (CHEBI:78741) has role neurotoxin (CHEBI:50910)
oxidopamine (CHEBI:78741) is a benzenetriol (CHEBI:22707)
oxidopamine (CHEBI:78741) is a catecholamine (CHEBI:33567)
oxidopamine (CHEBI:78741) is a primary amino compound (CHEBI:50994)
INNs Sources
oxidopamina ChemIDplus
oxidopamine WHO MedNet
oxidopamine ChemIDplus
oxidopaminum ChemIDplus
Synonyms Sources
2,4,5-trihydroxyphenethylamine ChemIDplus
6-hydroxydopamine ChemIDplus
6-OHDA ChemIDplus
hydroxydopamine MetaCyc
topamine ChEBI
Manual Xrefs Databases
CPD-7666 MetaCyc
HMDB0001537 HMDB
Oxidopamine Wikipedia
View more database links
Registry Number Type Source
2211011 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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22789904 PubMed citation Europe PMC
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23670213 PubMed citation Europe PMC
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Last Modified
26 February 2016