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patulin (CHEBI:74926)

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ChEBI Name patulin
ChEBI ID CHEBI:74926
Definition A furopyran and lactone that is 2H-pyran-3(6H)-ylidene)acetic acid which is syubstituted by hydroxy groups at positions 2 and 4 and in which the hydroxy group at position 4 has condensed with the carboxy group to give the corresponding bicyclic lactone. A mycotoxin produced by several species of Aspergillus and Penicillium, it has antibiotic properties but has been shown to be carcinogenic and mutagenic.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula Source
C7H6O4 ChEBI
Net Charge 0
Average Mass 154.12010
InChI
InChI=1S/C7H6O4/c8-6-3-4-5(11-6)1-2-10-7(4)9/h1,3,7,9H,2H2
InChIKey
ZRWPUFFVAOMMNM-UHFFFAOYSA-N
SMILES
OC1OCC=C2OC(=O)C=C12
Roles Classification
Biological Role(s): antibiotic
A substance that is biostatic or biocidal at low concentrations towards bacteria, yeasts, moulds, or other form of life, especially pathogenic or noxious organisms. Although the term was originally restricted to substances produced by microorganisms, its use was later expanded to include derivatives of such substances and it is now commonly used to include entirely synthetic compounds.
mycotoxin
Poisonous substance produced by fungi.
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
mutagen
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
Penicillium secondary metabolite
A fungal secondary metabolite that is not directly involved in the normal growth, development or reproduction of Penicillium.
Aspergillus secondary metabolite
A fungal secondary metabolite that is not directly involved in the normal growth, development or reproduction of Aspergillus .
Application(s): antibiotic
A substance that is biostatic or biocidal at low concentrations towards bacteria, yeasts, moulds, or other form of life, especially pathogenic or noxious organisms. Although the term was originally restricted to substances produced by microorganisms, its use was later expanded to include derivatives of such substances and it is now commonly used to include entirely synthetic compounds.
View more on the ChEBI Ontology
ChEBI Ontology
Outgoing patulin (CHEBI:74926) has role Aspergillus secondary metabolite (CHEBI:75864)
patulin (CHEBI:74926) has role Penicillium secondary metabolite (CHEBI:76205)
patulin (CHEBI:74926) has role antibiotic (CHEBI:22582)
patulin (CHEBI:74926) has role carcinogenic agent (CHEBI:50903)
patulin (CHEBI:74926) has role mutagen (CHEBI:25435)
patulin (CHEBI:74926) has role mycotoxin (CHEBI:25442)
patulin (CHEBI:74926) is a γ-lactone (CHEBI:37581)
patulin (CHEBI:74926) is a furopyran (CHEBI:74927)
patulin (CHEBI:74926) is a lactol (CHEBI:38131)
IUPAC Name
4-hydroxy-4H-furo[3,2-c]pyran-2(6H)-one
Synonyms Sources
(2,4-dihydroxy-2H-pyran-3(6H)-ylidene)acetic acid, 3,4-lactone ChemIDplus
(2,4-dihydroxy-2H-pyran-3(6H)-ylidene)acetic acid-3,4-lactone ChemIDplus
4,6-dihydro-4-hydroxy-2H-furo(3,2-c)pyran-2-one ChemIDplus
clavacin ChemIDplus
clavatin ChemIDplus
claviform ChemIDplus
claviformin ChemIDplus
expansin ChemIDplus
expansine ChemIDplus
mycoin C3 ChemIDplus
mycoine C3 ChemIDplus
PAT ChEBI
patuline ChemIDplus
Database Links Databases
C16748 KEGG COMPOUND
HMDB34299 HMDB
Patulin Wikipedia
US2417584 Patent
View more database links
Registry Numbers Types Sources
149-29-1 CAS Registry Number KEGG COMPOUND
149-29-1 CAS Registry Number ChemIDplus
149675 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
21656641 PubMed citation CiteXplore
22410236 PubMed citation CiteXplore
22988003 PubMed citation CiteXplore
23192667 PubMed citation CiteXplore
23384314 PubMed citation CiteXplore
23416552 PubMed citation CiteXplore
23729413 PubMed citation CiteXplore
23813870 PubMed citation CiteXplore
23870868 PubMed citation CiteXplore
Last Modified
13 January 2014

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