CHEBI:7449 - nafenopin

Main ChEBI Ontology Automatic Xrefs
ChEBI Name nafenopin
ChEBI ID CHEBI:7449
Definition A racemate comprising equimolar amounts of (R)- and (S)-nafenopin. It is a peroxisome proliferator that is used experimentally to promote liver tumors. It has been used as an hypolipidemic agent.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Biological Role(s): PPARalpha agonist
A PPAR modulator which activates the peroxisome proliferator-activated receptor-alpha.
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
Application(s): antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing nafenopin (CHEBI:7449) has part (R)-nafenopin (CHEBI:77650)
nafenopin (CHEBI:7449) has part (S)-nafenopin (CHEBI:77651)
nafenopin (CHEBI:7449) has role antilipemic drug (CHEBI:35679)
nafenopin (CHEBI:7449) has role carcinogenic agent (CHEBI:50903)
nafenopin (CHEBI:7449) has role PPARα agonist (CHEBI:70782)
nafenopin (CHEBI:7449) is a racemate (CHEBI:60911)
IUPAC Name
rac-2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid
INNs Sources
nafenopin WHO MedNet
nafenopina WHO MedNet
nafénopine WHO MedNet
nafenopinum WHO MedNet
Synonyms Sources
(±)-nafenopin ChEBI
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propionic acid ChEBI
2-methyl-2-[p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid ChEBI
2-methyl-2-[p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propionic acid ChemIDplus
α-methyl-α-(p-1,2,3,4-tetrahydronaphth-1-ylphenoxy)propionic acid ChemIDplus
C 13437 SU ChemIDplus
CH 13-437 ChemIDplus
CH 13437 ChemIDplus
Ciba 13437 SU ChemIDplus
D,L-nafenopin ChEBI
dl-nafenopin ChEBI
DL-nafenopin ChEBI
SU-13437 ChemIDplus
Brand Names Sources
Melipan ChemIDplus
SU 13437 ChemIDplus
Database Links Databases
C11371 KEGG COMPOUND
D05102 KEGG DRUG
DE2018135 Patent
Nafenopin Wikipedia
View more database links
Registry Numbers Types Sources
2005820 Reaxys Registry Number Reaxys
3771-19-5 CAS Registry Number KEGG COMPOUND
3771-19-5 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10383891 PubMed citation CiteXplore
10573520 PubMed citation CiteXplore
10726969 PubMed citation CiteXplore
10869456 PubMed citation CiteXplore
10903494 PubMed citation CiteXplore
10964109 PubMed citation CiteXplore
11133804 PubMed citation CiteXplore
18079279 PubMed citation CiteXplore
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Last Modified
11 March 2014