CHEBI:70007 - pachypodol

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ChEBI Name pachypodol
ChEBI ID CHEBI:70007
Definition A trimethoxyflavone that is quercetin in which the hydroxy groups at position 3, 7 and 3ʼ are replaced by methoxy groups. It has been isolated from Combretum quadrangulare and Euodia elleryana.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:7885
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Formula C18H16O7
Net Charge 0
Average Mass 344.31540
Monoisotopic Mass 344.090
InChI InChI=1S/C18H16O7/c1-22-10-7-12(20)15-14(8-10)25-17(18(24-3)16(15)21)9-4-5-11(19)13(6-9)23-2/h4-8,19-20H,1-3H3
InChIKey KQFUXLQBMQGNRT-UHFFFAOYSA-N
SMILES COc1cc(O)c2c(c1)oc(-c1ccc(O)c(OC)c1)c(OC)c2=O
Metabolite of Species Details
Combretum quadrangulare (IPNI:170410-1) Found in leaf (BTO:0000713). Methanolic extract of leaves See: PubMed
Euodia elleryana (IPNI:772987-1) MeOH-CH2Cl2(1:1)extract of dried, ground plant material,synonym Euodia is captured instead of Evodia See: PubMed
Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
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ChEBI Ontology
Outgoing pachypodol (CHEBI:70007) has functional parent quercetin (CHEBI:16243)
pachypodol (CHEBI:70007) has role antiemetic (CHEBI:50919)
pachypodol (CHEBI:70007) has role plant metabolite (CHEBI:76924)
pachypodol (CHEBI:70007) is a dihydroxyflavone (CHEBI:38686)
pachypodol (CHEBI:70007) is a trimethoxyflavone (CHEBI:27124)
IUPAC Name
5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one
Synonyms Sources
5,4ʼ-dihydroxy-3,7,3ʼ-quercetol trimethyl ether ChemIDplus
5,4ʼ-dihydroxy-3,7,3ʼ-trimethoxyflavone ChEBI
Quercetin 3,7,3'-trimethyl ether KEGG COMPOUND
Database Links Databases
C00004646 KNApSAcK
C10117 KEGG COMPOUND
LMPK12112754 LIPID MAPS
Pachypodol Wikipedia
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Registry Numbers Types Sources
33708-72-4 CAS Registry Number KEGG COMPOUND
33708-72-4 CAS Registry Number ChemIDplus
344651 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
10374246 PubMed citation Europe PMC
10725128 PubMed citation Europe PMC
11141110 PubMed citation Europe PMC
11199132 PubMed citation Europe PMC
16478239 PubMed citation Europe PMC
18570232 PubMed citation Europe PMC
21265555 PubMed citation Europe PMC
21275386 PubMed citation Europe PMC
22624328 PubMed citation Europe PMC
4201538 PubMed citation Europe PMC
Last Modified
28 July 2014