CHEBI:68437 - 5,6,7,8-tetrahydrofolate(2−)

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ChEBI Name 5,6,7,8-tetrahydrofolate(2−)
ChEBI ID CHEBI:68437
ChEBI ASCII Name 5,6,7,8-tetrahydrofolate(2-)
Definition A dicarboxylic acid anion arising from deprotonation of both carboxylic acid functions of 5,6,7,8-tetrahydrofolic acid; major structure at pH 7.3
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anne Morgat
Supplier Information
Download Molfile XML SDF
Formula C19H21N7O6
Net Charge -2
Average Mass 443.41330
Monoisotopic Mass 443.15643
InChI InChI=1S/C19H23N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,11-12,21,23H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/p-2/t11?,12-/m0/s1
InChIKey MSTNYGQPCMXVAQ-KIYNQFGBSA-L
SMILES Nc1nc2NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)Nc2c(=O)[nH]1
ChEBI Ontology
Outgoing 5,6,7,8-tetrahydrofolate(2−) (CHEBI:68437) is a dicarboxylic acid dianion (CHEBI:28965)
5,6,7,8-tetrahydrofolate(2−) (CHEBI:68437) is a tetrahydrofolate (CHEBI:67016)
5,6,7,8-tetrahydrofolate(2−) (CHEBI:68437) is conjugate base of 5,6,7,8-tetrahydrofolic acid (CHEBI:20506)
Incoming 5,6,7,8-tetrahydrofolic acid (CHEBI:20506) is conjugate acid of 5,6,7,8-tetrahydrofolate(2−) (CHEBI:68437)
IUPAC Name
(2S)-2-[(4-{[(2-amino-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzoyl)amino]pentanedioate
Synonym Source
5,6,7,8-tetrahydrofolate UniProt
Registry Number Type Source
21098913 Reaxys Registry Number Reaxys
Last Modified
20 March 2014