CHEBI:6704 - mebendazole

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ChEBI Name mebendazole
ChEBI ID CHEBI:6704
Definition A carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a benzoyl group at position 5.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C16H13N3O3
Net Charge 0
Average Mass 295.29284
InChI InChI=1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)
InChIKey OPXLLQIJSORQAM-UHFFFAOYSA-N
SMILES COC(=O)Nc1nc2cc(ccc2[nH]1)C(=O)c1ccccc1
Roles Classification
Biological Role(s): tubulin modulator
Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules.
microtubule-destabilising agent
Any substance that interacts with tubulin to inhibit polymerisation of microtubules.
Application(s): antinematodal drug
A substance used in the treatment or control of nematode infestations.
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ChEBI Ontology
Outgoing mebendazole (CHEBI:6704) has parent hydride 1H-benzimidazole (CHEBI:41275)
mebendazole (CHEBI:6704) has role antinematodal drug (CHEBI:35444)
mebendazole (CHEBI:6704) has role microtubule-destabilising agent (CHEBI:61951)
mebendazole (CHEBI:6704) has role tubulin modulator (CHEBI:60832)
mebendazole (CHEBI:6704) is a aromatic ketone (CHEBI:76224)
mebendazole (CHEBI:6704) is a benzimidazoles (CHEBI:22715)
mebendazole (CHEBI:6704) is a carbamate ester (CHEBI:23003)
IUPAC Name
methyl (5-benzoyl-1H-benzimidazol-2-yl)carbamate
Synonyms Sources
(5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester ChemIDplus
MBDZ ChemIDplus
Mebendazole KEGG COMPOUND
Vermox ChemIDplus
Database Links Databases
D00368 KEGG DRUG
DB00643 DrugBank
Mebendazole Wikipedia
View more database links
Registry Numbers Types Sources
31431-39-7 CAS Registry Number ChemIDplus
759809 Beilstein Registry Number Beilstein
759809 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
6126101 PubMed citation CiteXplore
Last Modified
18 February 2015