CHEBI:65737 - demethoxycurcumin

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ChEBI Name demethoxycurcumin
ChEBI ID CHEBI:65737
Definition A β-diketone that is curcumin in which one of the methoxy groups is replaced by hydrogen. It is found in Curcuma zedoaria and Etlingera elatior.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C20H18O5
Net Charge 0
Average Mass 338.35390
Monoisotopic Mass 338.115
InChI InChI=1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+
InChIKey HJTVQHVGMGKONQ-LUZURFALSA-N
SMILES COc1cc(\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2)ccc1O
Metabolite of Species Details
Curcuma zedoaria (NCBI:txid136224) See: PubMed
Etlingera elatior (NCBI:txid188493) Found in rhizome (BTO:0001181). See: PubMed
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
(via diarylheptanoid )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
anti-inflammatory agent
Any compound that has anti-inflammatory effects.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing demethoxycurcumin (CHEBI:65737) has role anti-inflammatory agent (CHEBI:67079)
demethoxycurcumin (CHEBI:65737) has role antineoplastic agent (CHEBI:35610)
demethoxycurcumin (CHEBI:65737) has role metabolite (CHEBI:25212)
demethoxycurcumin (CHEBI:65737) is a β-diketone (CHEBI:67265)
demethoxycurcumin (CHEBI:65737) is a diarylheptanoid (CHEBI:78802)
demethoxycurcumin (CHEBI:65737) is a enone (CHEBI:51689)
demethoxycurcumin (CHEBI:65737) is a polyphenol (CHEBI:26195)
IUPAC Name
(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione
Synonyms Sources
(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione ChEBI
(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-hepta-1,6-diene-3,5-dione ChEBI
4-hydroxycinnamoyl(feroyl)methane ChemIDplus
4-hydroxycinnamoyl(feruloyl)methane ChEBI
BHCFM ChemIDplus
curcuminII ChEBI
demethoxycurcumin UniProt
feruloyl-p-hydroxycinnnamoylmethane ChEBI
Manual Xrefs Databases
C17742 KEGG COMPOUND
CPD-12187 MetaCyc
View more database links
Registry Numbers Types Sources
22608-11-3 CAS Registry Number KEGG COMPOUND
24939-17-1 CAS Registry Number ChemIDplus
5589254 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
12059141 PubMed citation Europe PMC
15730265 PubMed citation Europe PMC
17553917 PubMed citation Europe PMC
18449507 PubMed citation Europe PMC
18826228 PubMed citation Europe PMC
19818349 PubMed citation Europe PMC
22454662 PubMed citation Europe PMC
22552297 PubMed citation Europe PMC
Last Modified
04 August 2014