CHEBI:65310 - triciribine

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ChEBI Name triciribine
Definition A nucleoside analogue in which the nucleobase portion is a 1,4,5,6,8-pentaazaacenaphthylene ring system substituted with an amino group at position 3, and a methyl group at position 5 and is bound to the β-D-ribofuranosyl moiety by an N1-glycosidic linkage.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C13H16N6O4
Net Charge 0
Average Mass 320.30390
Monoisotopic Mass 320.12330
InChI InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1
SMILES Cn1nc(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c3ncnc1c23
Roles Classification
Biological Role(s): EC (phosphatidylinositol 3-kinase) inhibitor
An inhibitor of phosphatidylinositol 3-kinase, EC, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing triciribine (CHEBI:65310) has role EC (phosphatidylinositol 3-kinase) inhibitor (CHEBI:50914)
triciribine (CHEBI:65310) is a nucleoside analogue (CHEBI:60783)
Synonym Source
TCN NIST Chemistry WebBook
Manual Xref Database
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Registry Numbers Types Sources
1171593 Reaxys Registry Number Reaxys
35943-35-2 CAS Registry Number ChemIDplus
35943-35-2 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
22075556 PubMed citation Europe PMC
22728437 PubMed citation Europe PMC
22773664 PubMed citation Europe PMC
Last Modified
25 February 2016