CHEBI:6484 - liothyronine sodium

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ChEBI Name liothyronine sodium
ChEBI ID CHEBI:6484
Definition The sodium salt of liothyronine. Thought to be more active than levothyroxine and with a rapid (few hours) onset and short duration of action, liothyronine sodium is used in the treatment of hypothyroidism, particularly in cases of hypothyroid coma.
Stars This entity has been manually annotated by the ChEBI Team.
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Formulae C15H11I3NNaO4
C15H11I3NO4.Na
Net Charge 0
Average Mass 672.95530
Monoisotopic Mass 672.772
InChI InChI=1S/C15H12I3NO4.Na/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22;/h1-4,6,12,20H,5,19H2,(H,21,22);/q;+1/p-1/t12-;/m0./s1
InChIKey SBXXSUDPJJJJLC-YDALLXLXSA-M
SMILES [Na+].N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C([O-])=O
ChEBI Ontology
Outgoing liothyronine sodium (CHEBI:6484) has part 3,3',5-triiodo-L-thyroninate (CHEBI:60308)
liothyronine sodium (CHEBI:6484) is a organic sodium salt (CHEBI:38700)
IUPAC Name
sodium (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
Synonyms Sources
3,3',5-Triiodo-L-thyronine sodium ChemIDplus
3,3',5-Triiodothyronine sodium salt ChemIDplus
Monosodium L-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine ChemIDplus
Brand Names Sources
Cytomel DrugBank
Tertroxin Deprecated term DrugBank
Tresitope Deprecated term DrugBank
Triostat DrugBank
Manual Xrefs Databases
D01011 KEGG DRUG
Liothyronine_Sodium Wikipedia
US2002193440 Patent
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Registry Numbers Types Sources
55-06-1 CAS Registry Number ChemIDplus
8179867 Reaxys Registry Number Reaxys
8179867 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
17634708 PubMed citation Europe PMC
28599168 PubMed citation Europe PMC
29216618 PubMed citation Europe PMC
Last Modified
30 April 2018