CHEBI:63624 - telbivudine

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ChEBI Name telbivudine
Definition A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Anonymous
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Formula C10H14N2O5
Net Charge 0
Average Mass 242.22860
Monoisotopic Mass 242.09027
InChI InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
SMILES Cc1cn([C@@H]2C[C@@H](O)[C@H](CO)O2)c(=O)[nH]c1=O
Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
EC (RNA-directed DNA polymerase) inhibitor
A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC, a viral DNA polymerase enzyme that retroviruses need in order to reproduce.
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
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ChEBI Ontology
Outgoing telbivudine (CHEBI:63624) has functional parent thymine (CHEBI:17821)
telbivudine (CHEBI:63624) has role antiviral drug (CHEBI:36044)
telbivudine (CHEBI:63624) has role EC (RNA-directed DNA polymerase) inhibitor (CHEBI:59897)
telbivudine (CHEBI:63624) is a pyrimidine 2'-deoxyribonucleoside (CHEBI:19255)
telbivudine (CHEBI:63624) is enantiomer of thymidine (CHEBI:17748)
Incoming thymidine (CHEBI:17748) is enantiomer of telbivudine (CHEBI:63624)
INN Source
telbivudine KEGG DRUG
Synonyms Sources
1-(2-deoxy-β-L-ribofuranosyl)-5-methyluracil ChEBI
2'-Deoxy-L-thymidine DrugBank
β-L-2'-deoxythymidine ChEBI
Beta-l-thymidine DrugBank
Epavudine DrugBank
L-deoxythymidine DrugBank
L-DT DrugBank
L-thymidine DrugBank
LDT DrugBank
Manual Xrefs Databases
4220 DrugCentral
DB01265 DrugBank
Telbivudine Wikipedia
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Registry Numbers Types Sources
3424-98-4 CAS Registry Number ChemIDplus
754297 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017