CHEBI:60269 - trisodium phosphonoformate hexahydrate

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ChEBI Name trisodium phosphonoformate hexahydrate
Definition The hexahydrate form of trisodium phosphonoformate. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula CH12Na3O11P
Net Charge 0
Average Mass 300.04240
Monoisotopic Mass 299.98103
InChI InChI=1S/CH3O5P.3Na.6H2O/c2-1(3)7(4,5)6;;;;;;;;;/h(H,2,3)(H2,4,5,6);;;;6*1H2/q;3*+1;;;;;;/p-3
SMILES O.O.O.O.O.O.[Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O
Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
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ChEBI Ontology
Outgoing trisodium phosphonoformate hexahydrate (CHEBI:60269) has part trisodium phosphonoformate (CHEBI:141644)
trisodium phosphonoformate hexahydrate (CHEBI:60269) has role antiviral drug (CHEBI:36044)
trisodium phosphonoformate hexahydrate (CHEBI:60269) is a hydrate (CHEBI:35505)
trisodium phosphonoformate hexahydrate (CHEBI:60269) is a one-carbon compound (CHEBI:64708)
Synonyms Sources
foscarnet sodium hexahydrate KEGG DRUG
trisodium phosphonoformate hexahydrate KEGG DRUG
Manual Xrefs Databases
DB00529 DrugBank
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Registry Numbers Types Sources
34156-56-4 CAS Registry Number ChemIDplus
34156-56-4 CAS Registry Number KEGG DRUG
Last Modified
12 June 2012