CHEBI:50223 - (+)-dexrazoxane

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ChEBI Name (+)-dexrazoxane
ChEBI ID CHEBI:50223
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C11H16N4O4
Net Charge 0
Average Mass 268.26930
Monoisotopic Mass 268.117
InChI InChI=1S/C11H16N4O4/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19)/t7-/m0/s1
InChIKey BMKDZUISNHGIBY-ZETCQYMHSA-N
SMILES C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
Roles Classification
Chemical Role(s): chelator
A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate.
Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
cardiovascular drug
A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
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ChEBI Ontology
Outgoing (+)-dexrazoxane (CHEBI:50223) has role antineoplastic agent (CHEBI:35610)
(+)-dexrazoxane (CHEBI:50223) has role cardiovascular drug (CHEBI:35554)
(+)-dexrazoxane (CHEBI:50223) has role chelator (CHEBI:38161)
(+)-dexrazoxane (CHEBI:50223) has role immunosuppressive agent (CHEBI:35705)
(+)-dexrazoxane (CHEBI:50223) is a razoxane (CHEBI:50225)
Incoming dexrazoxane hydrochloride (CHEBI:50224) has part (+)-dexrazoxane (CHEBI:50223)
IUPAC Name
4,4'-(2S)-propane-1,2-diyldipiperazine-2,6-dione
INNs Sources
dexrazoxane ChemIDplus
dexrazoxano ChemIDplus
dexrazoxanum ChemIDplus
Synonyms Sources
(+)-(S)-4,4'-Propylenedi-2,6-piperazinedione ChemIDplus
(+)-1,2-Bis(3,5-dioxo-1-piperazinyl)propane ChemIDplus
Dextrorazoxane DrugBank
Manual Xrefs Databases
839 DrugCentral
D03730 KEGG DRUG
DB00380 DrugBank
Dexrazoxane Wikipedia
LSM-5248 LINCS
View more database links
Registry Numbers Types Sources
24584-09-6 CAS Registry Number ChemIDplus
6658412 Beilstein Registry Number Beilstein
8441732 Beilstein Registry Number Beilstein
Last Modified
22 February 2017