CHEBI:44369 - duvoglustat

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ChEBI Name duvoglustat
ChEBI ID CHEBI:44369
Definition An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter qingping liu
qingping liu
Secondary ChEBI IDs CHEBI:132398, CHEBI:76525, CHEBI:132867
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Formula C6H13NO4
Net Charge 0
Average Mass 163.17170
Monoisotopic Mass 163.084
InChI InChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1
InChIKey LXBIFEVIBLOUGU-JGWLITMVSA-N
SMILES OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
Metabolite of Species Details
Bacillus amyloliquefaciens (NCBI:txid1390) See: PubMed
Bacillus subtilis (NCBI:txid1423) See: PubMed
Moraceae (NCBI:txid3487) See: PubMed
Morus alba (NCBI:txid3498) Found in latex (BTO:0000710). See: PubMed
Roles Classification
Biological Role(s): EC 3.2.1.20 (alpha-glucosidase) inhibitor
An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-glucosidase (EC 3.2.1.20).
anti-HIV agent
An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
anti-obesity agent
Any substance which is used to reduce or control weight.
bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): hypoglycemic agent
A drug which lowers the blood glucose level.
hepatoprotective agent
Any compound that is able to prevent damage to the liver.
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ChEBI Ontology
Outgoing duvoglustat (CHEBI:44369) has role anti-HIV agent (CHEBI:64946)
duvoglustat (CHEBI:44369) has role anti-obesity agent (CHEBI:74518)
duvoglustat (CHEBI:44369) has role bacterial metabolite (CHEBI:76969)
duvoglustat (CHEBI:44369) has role EC 3.2.1.20 (α-glucosidase) inhibitor (CHEBI:67239)
duvoglustat (CHEBI:44369) has role hepatoprotective agent (CHEBI:62868)
duvoglustat (CHEBI:44369) has role hypoglycemic agent (CHEBI:35526)
duvoglustat (CHEBI:44369) has role plant metabolite (CHEBI:76924)
duvoglustat (CHEBI:44369) is a 2-(hydroxymethyl)piperidine-3,4,5-triol (CHEBI:72490)
Incoming 4-O-α-D-glucopyranosylmoranoline (CHEBI:70736) has functional parent duvoglustat (CHEBI:44369)
N-nonyldeoxynojirimycin (CHEBI:76399) has functional parent duvoglustat (CHEBI:44369)
miglustat (CHEBI:50381) has functional parent duvoglustat (CHEBI:44369)
IUPAC Name
(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
INN Source
duvoglustat KEGG DRUG
Synonyms Sources
(+)-1-Deoxynojirimycin KNApSAcK
1,5-deoxy-1,5-imino-D-mannitol DrugBank
1,5-dideoxy-1,5-imino-D-glucitol DrugBank
1-Deoxymannojirimycin DrugBank
1-Deoxynojirimycin KEGG DRUG
1-DEOXYNOJIRIMYCIN PDBeChem
5-amino-1,5-dideoxy-D-glucopyranose DrugBank
BAY-H-5595 DrugBank
D-1-deoxynojirimycin DrugBank
DNJ DrugBank
Moranolin KEGG COMPOUND
Moranoline ChemIDplus
Manual Xrefs Databases
1-Deoxynojirimycin Wikipedia
1-DEOXYNOJIRIMYCIN MetaCyc
C00029420 KNApSAcK
C16843 KEGG COMPOUND
D09605 KEGG DRUG
DB03206 DrugBank
HMDB0035359 HMDB
NOJ PDBeChem
View more database links
Registry Numbers Types Sources
1524395 Reaxys Registry Number Reaxys
19130-96-2 CAS Registry Number KEGG COMPOUND
19130-96-2 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
23265519 PubMed citation Europe PMC
23391926 PubMed citation Europe PMC
23536174 PubMed citation Europe PMC
23561072 PubMed citation Europe PMC
23570294 PubMed citation Europe PMC
23648852 PubMed citation Europe PMC
23755289 PubMed citation Europe PMC
23909841 PubMed citation Europe PMC
24050301 PubMed citation Europe PMC
26292150 PubMed citation Europe PMC
26867190 PubMed citation Europe PMC
26927057 PubMed citation Europe PMC
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27294120 PubMed citation Europe PMC
Last Modified
30 January 2017