CHEBI:42223 - emodin

Main ChEBI Ontology Automatic Xrefs
ChEBI Name emodin
ChEBI ID CHEBI:42223
Definition A member of the class of hydroxyanthraquinones that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42221, CHEBI:4782
Supplier Information
Save molfile Download Molfile
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C15H10O5
Net Charge 0
Average Mass 270.23690
InChI InChI=1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
InChIKey RHMXXJGYXNZAPX-UHFFFAOYSA-N
SMILES Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1
Metabolite of Species Details
Microdiplodia (NCBI:371130) EtOAc extract of an endophytic fungi isolated from Lycium intricatum of strain 9907 See: PubMed
Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
tyrosine kinase inhibitor
Any protein kinase inhibitor that interferes with the action of tyrosine kinase.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
laxative
An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing emodin (CHEBI:42223) has role antineoplastic agent (CHEBI:35610)
emodin (CHEBI:42223) has role laxative (CHEBI:50503)
emodin (CHEBI:42223) has role plant metabolite (CHEBI:76924)
emodin (CHEBI:42223) has role tyrosine kinase inhibitor (CHEBI:38637)
emodin (CHEBI:42223) is a hydroxyanthraquinones (CHEBI:37485)
emodin (CHEBI:42223) is conjugate acid of emodin(1−) (CHEBI:77659)
Incoming questin (CHEBI:16200) has functional parent emodin (CHEBI:42223)
emodin(1−) (CHEBI:77659) is conjugate base of emodin (CHEBI:42223)
IUPAC Name
1,3,8-trihydroxy-6-methylanthra-9,10-quinone
Synonyms Sources
1,3,8-trihydroxy-6-methyl-9,10-anthracenedione ChemIDplus
1,3,8-trihydroxy-6-methyl-9,10-anthraquinone ChemIDplus
3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE PDBeChem
Emodin KEGG COMPOUND
Schuttgelb ChemIDplus
Database Links Databases
C00000555 KNApSAcK
C10343 KEGG COMPOUND
DB07715 DrugBank
EMO PDBeChem
Emodin Wikipedia
LMPK13040008 LIPID MAPS
View more database links
Registry Numbers Types Sources
1888141 Beilstein Registry Number ChemIDplus
1888141 Reaxys Registry Number Reaxys
518-82-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12563347 PubMed citation CiteXplore
12657721 PubMed citation CiteXplore
16077936 PubMed citation CiteXplore
16388516 PubMed citation CiteXplore
16959273 PubMed citation CiteXplore
17019678 PubMed citation CiteXplore
17022020 PubMed citation CiteXplore
17340270 PubMed citation CiteXplore
18193729 PubMed citation CiteXplore
18387517 PubMed citation CiteXplore
18473931 PubMed citation CiteXplore
19089830 PubMed citation CiteXplore
19409890 PubMed citation CiteXplore
19505457 PubMed citation CiteXplore
19799875 PubMed citation CiteXplore
19921750 PubMed citation CiteXplore
20139316 PubMed citation CiteXplore
21834668 PubMed citation CiteXplore
22020806 PubMed citation CiteXplore
22137788 PubMed citation CiteXplore
22144110 PubMed citation CiteXplore
22271272 PubMed citation CiteXplore
22378302 PubMed citation CiteXplore
22426603 PubMed citation CiteXplore
22452333 PubMed citation CiteXplore
22484343 PubMed citation CiteXplore
Last Modified
28 July 2014