User Survey : Help improve ChEBI - please click here to take part in our quick User Survey.

CHEBI:41948 - 2-(difluoromethyl)ornithine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 2-(difluoromethyl)ornithine
ChEBI ID CHEBI:41948
Definition A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:41946, CHEBI:4761
Supplier Information
Save molfile Download Molfile
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C6H12F2N2O2
Net Charge 0
Average Mass 182.16850
Monoisotopic Mass 182.087
InChI InChI=1S/C6H12F2N2O2/c7-4(8)6(10,5(11)12)2-1-3-9/h4H,1-3,9-10H2,(H,11,12)
InChIKey VLCYCQAOQCDTCN-UHFFFAOYSA-N
SMILES NCCCC(N)(C(F)F)C(O)=O
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
Application(s): trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 2-(difluoromethyl)ornithine (CHEBI:41948) has functional parent ornithine (CHEBI:18257)
2-(difluoromethyl)ornithine (CHEBI:41948) has role trypanocidal drug (CHEBI:36335)
2-(difluoromethyl)ornithine (CHEBI:41948) is a fluoroamino acid (CHEBI:24068)
IUPAC Names
2,5-diamino-2-(difluoromethyl)pentanoic acid
2-(difluoromethyl)ornithine
Synonyms Sources
α-difluoromethylornithine ChemIDplus
ALPHA-DIFLUOROMETHYLORNITHINE PDBeChem
DFMO ChemIDplus
DL-Ornithine, 2-(difluoromethyl)- KEGG COMPOUND
Eflornithine KEGG COMPOUND
Database Links Databases
C07997 KEGG COMPOUND
D07883 KEGG DRUG
DB03856 DrugBank
DMO PDBeChem
Eflornithine Wikipedia
View more database links
Registry Numbers Types Sources
2250529 Beilstein Registry Number ChemIDplus
2250529 Reaxys Registry Number Reaxys
67037-37-0 CAS Registry Number ChemIDplus
70052-12-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
16541214 PubMed citation Europe PMC
23771434 PubMed citation Europe PMC
24144414 PubMed citation Europe PMC
Last Modified
28 July 2014