CHEBI:3423 - carmustine

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ChEBI Name carmustine
ChEBI ID CHEBI:3423
Definition A member of the class of N-nitrosoureas that is 1,3-bis(2-chloroethyl)urea in which one of the nitrogens is substituted by a nitroso group.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C5H9Cl2N3O2
Net Charge 0
Average Mass 214.05000
Monoisotopic Mass 213.007
InChI InChI=1S/C5H9Cl2N3O2/c6-1-3-8-5(11)10(9-12)4-2-7/h1-4H2,(H,8,11)
InChIKey DLGOEMSEDOSKAD-UHFFFAOYSA-N
SMILES ClCCNC(=O)N(CCCl)N=O
Roles Classification
Biological Role(s): alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
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ChEBI Ontology
Outgoing carmustine (CHEBI:3423) has role alkylating agent (CHEBI:22333)
carmustine (CHEBI:3423) has role antineoplastic agent (CHEBI:35610)
carmustine (CHEBI:3423) is a N-nitrosoureas (CHEBI:76551)
carmustine (CHEBI:3423) is a organochlorine compound (CHEBI:36683)
IUPAC Name
1,3-bis(2-chloroethyl)-1-nitrosourea
INNs Sources
carmustina WHO MedNet
carmustine WHO MedNet
carmustine WHO MedNet
carmustinum WHO MedNet
Synonyms Sources
BCNU KEGG COMPOUND
Bicnu (TN) KEGG DRUG
Bischloroethyl nitrosourea KEGG COMPOUND
Carmustine KEGG DRUG
Gliadel ChemIDplus
N,N'-Bis(2-chloroethyl)-N-nitrosourea ChemIDplus
Manual Xrefs Databases
512 DrugCentral
Carmustine Wikipedia
D00254 KEGG DRUG
DB00262 DrugBank
View more database links
Registry Numbers Types Sources
154-93-8 CAS Registry Number ChemIDplus
154-93-8 CAS Registry Number KEGG DRUG
Last Modified
22 February 2017