CHEBI:32292 - vedaprofen

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ChEBI Name vedaprofen
ChEBI ID CHEBI:32292
Definition A racemate composed of equal amounts of (R)- and (S)-vedaprofen. Used for control of pain and inflammation particularly associated with chronic musculoskeletal disorders and soft tissue trauma in dogs and horses and for treatment of pain due to horse colic.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H22O2
Net Charge 0
Average Mass 282.377
Monoisotopic Mass 282.162
Roles Classification
Biological Role(s): EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor
A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
anti-ulcer drug
One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
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ChEBI Ontology
Outgoing vedaprofen (CHEBI:32292) has part (R)-vedaprofen (CHEBI:76285)
vedaprofen (CHEBI:32292) has part (S)-vedaprofen (CHEBI:76286)
vedaprofen (CHEBI:32292) has role anti-ulcer drug (CHEBI:49201)
vedaprofen (CHEBI:32292) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544)
vedaprofen (CHEBI:32292) has role non-narcotic analgesic (CHEBI:35481)
vedaprofen (CHEBI:32292) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
vedaprofen (CHEBI:32292) is a racemate (CHEBI:60911)
IUPAC Name
rac-2-(4-cyclohexyl-1-naphthyl)propanoic acid
INNs Sources
vedaprofen KEGG DRUG
védaprofène WHO MedNet
vedaprofeno WHO MedNet
vedaprofenum WHO MedNet
Synonyms Sources
(±)-4-cyclohexyl-α-methyl-1-naphthaleneacetic acid ChemIDplus
(±)-vedaprofen ChEBI
(RS)-vedaprofen ChEBI
DL-vedaprofen ChEBI
racemic vedaprofen ChEBI
Manual Xrefs Databases
1908 VSDB
2812 DrugCentral
D01874 KEGG DRUG
US4218473 Patent
Vedaprofen Wikipedia
View more database links
Registry Numbers Types Sources
5568831 Reaxys Registry Number Reaxys
71109-09-6 CAS Registry Number ChemIDplus
71109-09-6 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
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Last Modified
19 September 2018