CHEBI:31866 - mosapramine dihydrochloride

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ChEBI Name mosapramine dihydrochloride
ChEBI ID CHEBI:31866
Definition A racemate comprising equimolar amounts of (R)- and (S)-mosapramine dihydrochloride.
Stars This entity has been manually annotated by a third party.
Supplier Information
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Formulae C28H35ClN4O.2HCl
C28H35ClN4O.ClH.ClH
Net Charge 0
Average Mass 551.980
Monoisotopic Mass 550.20329
InChI InChI=1S/C28H35ClN4O.2ClH/c29-23-12-11-22-10-9-21-6-1-2-7-24(21)32(25(22)20-23)16-5-15-31-18-13-28(14-19-31)27(34)30-26-8-3-4-17-33(26)28;;/h1-2,6-7,11-12,20,26H,3-5,8-10,13-19H2,(H,30,34);2*1H
InChIKey CVCDAZZJQWLXHM-UHFFFAOYSA-N
SMILES Cl.Cl.ClC1=CC=C2CCC3=CC=CC=C3N(CCCN3CCC4(CC3)N3CCCCC3NC4=O)C2=C1
Roles Classification
Biological Role(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Application(s): dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
second generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be less likely than first generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing mosapramine dihydrochloride (CHEBI:31866) has role dopaminergic antagonist (CHEBI:48561)
mosapramine dihydrochloride (CHEBI:31866) has role second generation antipsychotic (CHEBI:65191)
mosapramine dihydrochloride (CHEBI:31866) is a racemate (CHEBI:60911)
IUPAC Name
rac-1'-[3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one dihydrochloride
Synonyms Sources
Cremin KEGG DRUG
mosapramine .2HCl ChEBI
mosapramine dihydrochloride KEGG DRUG
mosapramine hydrochloride ChemIDplus
Manual Xref Database
D01548 KEGG DRUG
View more database links
Registry Number Type Source
98043-60-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
8103712 PubMed citation Europe PMC
8690306 PubMed citation Europe PMC
Last Modified
14 January 2021