CHEBI:31783 - lornoxicam

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ChEBI Name lornoxicam
ChEBI ID CHEBI:31783
Definition A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations.
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Formula C13H10ClN3O4S2
Net Charge 0
Average Mass 371.81900
Monoisotopic Mass 370.98013
InChI InChI=1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChIKey WLHQHAUOOXYABV-UHFFFAOYSA-N
SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2sc(Cl)cc2S1(=O)=O
Roles Classification
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
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ChEBI Ontology
Outgoing lornoxicam (CHEBI:31783) has role antipyretic (CHEBI:35493)
lornoxicam (CHEBI:31783) has role non-narcotic analgesic (CHEBI:35481)
lornoxicam (CHEBI:31783) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
lornoxicam (CHEBI:31783) is a heteroaryl hydroxy compound (CHEBI:74818)
lornoxicam (CHEBI:31783) is a monocarboxylic acid amide (CHEBI:29347)
lornoxicam (CHEBI:31783) is a organochlorine compound (CHEBI:36683)
lornoxicam (CHEBI:31783) is a pyridines (CHEBI:26421)
lornoxicam (CHEBI:31783) is a thienothiazine (CHEBI:46977)
IUPAC Name
6-chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
INNs Sources
lornoxicam WHO MedNet
lornoxicam WHO MedNet
lornoxicam KEGG DRUG
lornoxicamum DrugBank
Synonyms Sources
CCRIS 8589 ChemIDplus
Chlortenoxicam ChemIDplus
Ro 13-9297 ChemIDplus
Manual Xrefs Databases
1609 DrugCentral
D01866 KEGG DRUG
DB06725 DrugBank
Lornoxicam Wikipedia
US2008014272 Patent
View more database links
Registry Numbers Types Sources
1039965 Beilstein Registry Number ChemIDplus
1039965 Reaxys Registry Number Reaxys
70374-39-9 CAS Registry Number ChemIDplus
70374-39-9 CAS Registry Number KEGG DRUG
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Last Modified
22 February 2017