CHEBI:31618 - fludiazepam

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name fludiazepam
ChEBI ID CHEBI:31618
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C16H12ClFN2O
Net Charge 0
Average Mass 302.73046
Monoisotopic Mass 302.062
InChI InChI=1S/C16H12ClFN2O/c1-20-14-7-6-10(17)8-12(14)16(19-9-15(20)21)11-4-2-3-5-13(11)18/h2-8H,9H2,1H3
InChIKey ROYOYTLGDLIGBX-UHFFFAOYSA-N
SMILES CN1C(=O)CN=C(c2ccccc2F)c2cc(Cl)ccc12
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
Application(s): anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via benzodiazepine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing fludiazepam (CHEBI:31618) has functional parent diazepam (CHEBI:49575)
fludiazepam (CHEBI:31618) has functional parent monofluorobenzene (CHEBI:5115)
fludiazepam (CHEBI:31618) has role anxiolytic drug (CHEBI:35474)
fludiazepam (CHEBI:31618) is a 1,4-benzodiazepinone (CHEBI:35500)
fludiazepam (CHEBI:31618) is a organochlorine compound (CHEBI:36683)
fludiazepam (CHEBI:31618) is a organofluorine compound (CHEBI:37143)
IUPAC Name
7-chloro-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Synonyms Sources
7-chloro-5-(o-Fluorophenyl)-1,3-dihydro-1-methyl-2H-1,4-benzodiazepin-2-one NIST Chemistry WebBook
Erispan NIST Chemistry WebBook
fludiazepam ChemIDplus
Manual Xrefs Databases
1190 DrugCentral
D01354 KEGG DRUG
DB01567 DrugBank
DE1136709 Patent
US3051701 Patent
View more database links
Registry Numbers Types Sources
3900-31-0 CAS Registry Number ChemIDplus
3900-31-0 CAS Registry Number NIST Chemistry WebBook
686115 Beilstein Registry Number Beilstein
Last Modified
22 February 2017