CHEBI:28973 - strychnine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name strychnine
ChEBI ID CHEBI:28973
Definition A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:9293, CHEBI:26795
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C21H22N2O2
Net Charge 0
Average Mass 334.41160
Monoisotopic Mass 334.168
InChI InChI=1S/C21H22N2O2/c24-18-10-16-19-13-9-17-21(6-7-22(17)11-12(13)5-8-25-16)14-3-1-2-4-15(14)23(18)20(19)21/h1-5,13,16-17,19-20H,6-11H2/t13-,16-,17-,19-,20-,21+/m0/s1
InChIKey QMGVPVSNSZLJIA-FVWCLLPLSA-N
SMILES [H][C@@]12CC(=O)N3c4ccccc4[C@]45CCN6CC(=CCO1)[C@]([H])(C[C@@]46[H])[C@]2([H])[C@]35[H]
Roles Classification
Biological Role(s): glycine receptor antagonist
An antagonist that blocks glycine receptors.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
neurotransmitter agent
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
Application(s): cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
neurotransmitter agent
A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.
rodenticide
A substance used to destroy rodent pests.
avicide
A substance used to destroy bird pests (class Aves).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing strychnine (CHEBI:28973) has parent hydride strychnidine (CHEBI:36337)
strychnine (CHEBI:28973) has role avicide (CHEBI:33289)
strychnine (CHEBI:28973) has role cholinergic antagonist (CHEBI:48873)
strychnine (CHEBI:28973) has role glycine receptor antagonist (CHEBI:62754)
strychnine (CHEBI:28973) has role neurotransmitter agent (CHEBI:35942)
strychnine (CHEBI:28973) has role rodenticide (CHEBI:33288)
strychnine (CHEBI:28973) is a monoterpenoid indole alkaloid (CHEBI:65323)
strychnine (CHEBI:28973) is a organic heteroheptacyclic compound (CHEBI:52157)
strychnine (CHEBI:28973) is conjugate base of strychnine(1+) (CHEBI:90700)
Incoming α-colubrine (CHEBI:132696) has functional parent strychnine (CHEBI:28973)
β-colubrine (CHEBI:132697) has functional parent strychnine (CHEBI:28973)
2-hydroxy-3-methoxystrychnine (CHEBI:132705) has functional parent strychnine (CHEBI:28973)
pseudostrychnine (CHEBI:132666) has functional parent strychnine (CHEBI:28973)
strychnine N-oxide (CHEBI:132703) has functional parent strychnine (CHEBI:28973)
strychnine(1+) (CHEBI:90700) is conjugate acid of strychnine (CHEBI:28973)
IUPAC Name
strychnidin-10-one
Synonyms Sources
Strychnin ChemIDplus
Strychnine KEGG COMPOUND
Database Links Databases
2484 DrugCentral
C00001770 KNApSAcK
C00025213 KNApSAcK
C06522 KEGG COMPOUND
Strychnine Wikipedia
SY9 PDBeChem
View more database links
Registry Numbers Types Sources
117894 Gmelin Registry Number Gmelin
52979 Beilstein Registry Number Beilstein
52979 Reaxys Registry Number Reaxys
57-24-9 CAS Registry Number KEGG COMPOUND
57-24-9 CAS Registry Number ChemIDplus
57-24-9 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
10471592 PubMed citation Europe PMC
10821054 PubMed citation Europe PMC
11024105 PubMed citation Europe PMC
11157095 PubMed citation Europe PMC
11324564 PubMed citation Europe PMC
11327524 PubMed citation Europe PMC
11453337 PubMed citation Europe PMC
11516560 PubMed citation Europe PMC
11900860 PubMed citation Europe PMC
12611967 PubMed citation Europe PMC
12718443 PubMed citation Europe PMC
12742643 PubMed citation Europe PMC
12757728 PubMed citation Europe PMC
14530208 PubMed citation Europe PMC
14552874 PubMed citation Europe PMC
14575889 PubMed citation Europe PMC
15046720 PubMed citation Europe PMC
15275654 PubMed citation Europe PMC
15302677 PubMed citation Europe PMC
15601738 PubMed citation Europe PMC
15610168 PubMed citation Europe PMC
16075189 PubMed citation Europe PMC
16171972 PubMed citation Europe PMC
16887371 PubMed citation Europe PMC
16950410 PubMed citation Europe PMC
17145135 PubMed citation Europe PMC
17365101 PubMed citation Europe PMC
17449162 PubMed citation Europe PMC
17595105 PubMed citation Europe PMC
17827655 PubMed citation Europe PMC
17900376 PubMed citation Europe PMC
18199816 PubMed citation Europe PMC
19071748 PubMed citation Europe PMC
19194159 PubMed citation Europe PMC
19200346 PubMed citation Europe PMC
19394327 PubMed citation Europe PMC
19445923 PubMed citation Europe PMC
19617896 PubMed citation Europe PMC
19628662 PubMed citation Europe PMC
20534469 PubMed citation Europe PMC
20810461 PubMed citation Europe PMC
20837125 PubMed citation Europe PMC
21042643 PubMed citation Europe PMC
21109870 PubMed citation Europe PMC
21468359 PubMed citation Europe PMC
21506420 PubMed citation Europe PMC
21532268 PubMed citation Europe PMC
21616062 PubMed citation Europe PMC
21618309 PubMed citation Europe PMC
21666516 PubMed citation Europe PMC
21726589 PubMed citation Europe PMC
22168233 PubMed citation Europe PMC
22417832 PubMed citation Europe PMC
23395890 PubMed citation Europe PMC
25702781 PubMed citation Europe PMC
25877308 PubMed citation Europe PMC
25958869 PubMed citation Europe PMC
26028680 PubMed citation Europe PMC
26173662 PubMed citation Europe PMC
26223366 PubMed citation Europe PMC
26330182 PubMed citation Europe PMC
26416729 PubMed citation Europe PMC
26556179 PubMed citation Europe PMC
26625339 PubMed citation Europe PMC
9918589 PubMed citation Europe PMC
Last Modified
22 February 2017