CHEBI:17405 - 4-pyridoxic acid

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ChEBI Name 4-pyridoxic acid
Definition A methylpyridine that is 2-methylpyridine substituted by a hydroxy group at C-3, a carboxy group at C-4, and a hydroxymethyl group at C-5. It is the catabolic product of vitamin B6 and is excreted in the urine.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:1928, CHEBI:20474
Supplier Information
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Formula C8H9NO4
Net Charge 0
Average Mass 183.16140
Monoisotopic Mass 183.05316
InChI InChI=1S/C8H9NO4/c1-4-7(11)6(8(12)13)5(3-10)2-9-4/h2,10-11H,3H2,1H3,(H,12,13)
SMILES Cc1ncc(CO)c(C(O)=O)c1O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) Source: BioModels - MODEL1507180067 See: PubMed
Homo sapiens (NCBI:txid9606) See: PubMed
Homo sapiens (NCBI:txid9606) Found in saliva (UBERON:0001836). See: Dame, ZT. et al. (2014) The Human Saliva Metabolome (manuscript in preparation)
Homo sapiens (NCBI:txid9606) Found in urine (BTO:0001419). See: PubMed
Homo sapiens (NCBI:txid9606) Found in blood (UBERON:0000178). See: PubMed
Homo sapiens (NCBI:txid9606) From MetaboLights See: MetaboLights Study
Homo sapiens (NCBI:txid9606) From MetaboLights See: MetaboLights Study
Roles Classification
Biological Role(s): mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
human urinary metabolite
Any metabolite (endogenous or exogenous) found in human urine samples.
water-soluble vitamin (role)
Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine.
(via B vitamin )
Application(s): nutraceutical
A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance.
(via B vitamin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 4-pyridoxic acid (CHEBI:17405) has functional parent isonicotinic acid (CHEBI:6032)
4-pyridoxic acid (CHEBI:17405) has role human urinary metabolite (CHEBI:84087)
4-pyridoxic acid (CHEBI:17405) has role mouse metabolite (CHEBI:75771)
4-pyridoxic acid (CHEBI:17405) is a hydroxymethylpyridine (CHEBI:38196)
4-pyridoxic acid (CHEBI:17405) is a methylpyridines (CHEBI:25340)
4-pyridoxic acid (CHEBI:17405) is a monohydroxypyridine (CHEBI:38182)
4-pyridoxic acid (CHEBI:17405) is a vitamin B6 (CHEBI:27306)
4-pyridoxic acid (CHEBI:17405) is conjugate acid of 4-pyridoxate (CHEBI:30959)
Incoming 4-pyridoxolactone (CHEBI:16871) has functional parent 4-pyridoxic acid (CHEBI:17405)
4-pyridoxate (CHEBI:30959) is conjugate base of 4-pyridoxic acid (CHEBI:17405)
3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxylic acid
Synonyms Sources
2-methyl-3-hydroxy-4-carboxy-5-hydroxymethylpyridine ChemIDplus
3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxylic acid ChemIDplus
3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinic acid ChemIDplus
4-Pyridoxic acid KEGG COMPOUND
4-pyridoxinecarboxylic acid ChemIDplus
4-pyridoxinic acid ChemIDplus
4-Pyridoxinsaeure ChemIDplus
4-pyridoxylic acid ChemIDplus
pyridoxic acid ChemIDplus
Manual Xrefs Databases
6467 ChemSpider
C00052160 KNApSAcK
CPD-1112 MetaCyc
FDB021874 FooDB
HMDB0000017 HMDB
View more database links
Registry Numbers Types Sources
384006 Beilstein Registry Number Beilstein
384006 Reaxys Registry Number Reaxys
82-82-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
11756060 PubMed citation Europe PMC
1462525 PubMed citation Europe PMC
14747687 PubMed citation Europe PMC
1783639 PubMed citation Europe PMC
17868768 PubMed citation Europe PMC
22770225 PubMed citation Europe PMC
23535534 PubMed citation Europe PMC
2580028 PubMed citation Europe PMC
28778380 PubMed citation Europe PMC
30845778 PubMed citation Europe PMC
32346589 PubMed citation Europe PMC
8505768 PubMed citation Europe PMC
Last Modified
22 July 2021