CHEBI:135752 - tafenoquine

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ChEBI Name tafenoquine
ChEBI ID CHEBI:135752
Definition A racemate comprising equimolar amounts of (R)- and (S)-tafenoquine.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C24H28F3N3O3
Net Charge 0
Average Mass 463.494
Monoisotopic Mass 463.208
Roles Classification
Biological Role(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
apoptosis inducer
Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms.
Application(s): antimalarial
A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human.
antileishmanial agent
An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania.
trypanocidal drug
A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tafenoquine (CHEBI:135752) has part (R)-tafenoquine (CHEBI:141488)
tafenoquine (CHEBI:135752) has part (S)-tafenoquine (CHEBI:141489)
tafenoquine (CHEBI:135752) has role antileishmanial agent (CHEBI:70868)
tafenoquine (CHEBI:135752) has role antimalarial (CHEBI:38068)
tafenoquine (CHEBI:135752) has role apoptosis inducer (CHEBI:68495)
tafenoquine (CHEBI:135752) has role trypanocidal drug (CHEBI:36335)
tafenoquine (CHEBI:135752) is a racemate (CHEBI:60911)
IUPAC Name
rac-N4-{2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl}pentane-1,4-diamine
INNs Sources
tafenoquina WHO MedNet
tafenoquine ChemIDplus
tafénoquine WHO MedNet
tafenoquinum ChEBI
Synonyms Sources
etaquine ChEBI
WR 238,605 ChEBI
WR238605 ChEBI
Brand Names Sources
Arakoda ChEBI
Krintafel ChEBI
Manual Xrefs Databases
3578 DrugCentral
D10490 KEGG DRUG
DB06608 DrugBank
Tafenoquine Wikipedia
View more database links
Registry Numbers Types Sources
106635-80-7 CAS Registry Number DrugCentral
106635-80-7 CAS Registry Number ChemIDplus
6493037 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
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Last Modified
29 August 2018