CHEBI:66686 - maytenfolone A

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ChEBI Name maytenfolone A
ChEBI ID CHEBI:66686
Definition A hexacyclic triterpenoid that is a lactone of friedelin. Isolated from Celastrus hindsii, it exhibits anti-HIV and antineoplastic activities.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C30H46O4
Net Charge 0
Average Mass 470.68380
Monoisotopic Mass 470.33961
InChI InChI=1S/C30H46O4/c1-18-19(31)7-8-20-26(18,3)10-9-21-27(20,4)12-13-28(5)22-15-25(2)11-14-30(22,17-34-24(25)33)23(32)16-29(21,28)6/h18,20-23,32H,7-17H2,1-6H3/t18-,20+,21-,22-,23+,25-,26+,27-,28-,29+,30+/m0/s1
InChIKey BVZOXPCXYRGXKC-RUXXHOCVSA-N
SMILES [H][C@@]12CCC(=O)[C@H](C)[C@@]1(C)CC[C@@]1([H])[C@@]2(C)CC[C@@]2(C)[C@]3([H])C[C@]4(C)CC[C@]3(COC4=O)[C@H](O)C[C@]12C
Metabolite of Species Details
Celastrus hindsii (NCBI:txid489979) Found in stem (BTO:0001300). See: PubMed
Roles Classification
Biological Role(s): anti-HIV agent
An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing maytenfolone A (CHEBI:66686) has functional parent friedelin (CHEBI:5171)
maytenfolone A (CHEBI:66686) has role anti-HIV agent (CHEBI:64946)
maytenfolone A (CHEBI:66686) has role antineoplastic agent (CHEBI:35610)
maytenfolone A (CHEBI:66686) has role metabolite (CHEBI:25212)
maytenfolone A (CHEBI:66686) is a bridged compound (CHEBI:35990)
maytenfolone A (CHEBI:66686) is a cyclic terpene ketone (CHEBI:36130)
maytenfolone A (CHEBI:66686) is a hexacyclic triterpenoid (CHEBI:70994)
maytenfolone A (CHEBI:66686) is a secondary alcohol (CHEBI:35681)
maytenfolone A (CHEBI:66686) is a terpene lactone (CHEBI:37668)
IUPAC Name
(2S,5aS,6R,7aR,7bS,9aS,10R,13aS,13bS,15aS,15bS)-6-hydroxy-2,7a,9a,10,13b,15a-hexamethyloctadecahydro-2,5a-ethanochryseno[2,1-c]oxepine-3,11(5H)-dione
Registry Number Type Source
7666520 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
9115698 PubMed citation Europe PMC
Last Modified
05 April 2013