InChI=1S/C18H26O4/c1-11-5-6-12-3-2-4-16(20)18(12)15(11)8-7-14-9-13(19)10-17(21)22-14/h3,5-6,11,13-16,18-20H,2,4,7-10H2,1H3/t11-,13+,14+,15-,16-,18-/m0/s1 |
WWSNTLOVYSRDEL-DZSDEGEFSA-N |
C1CC=C2[C@]([C@H]1O)([C@H]([C@H](C=C2)C)CC[C@H]3OC(C[C@@H](C3)O)=O)[H] |
|
Penicillium citrinum
(NCBI:txid5077)
|
Found in
cell suspension culture
(BTO:0000221).
of strain
SANK 18767
See:
PubMed
|
fungal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds.
EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
|
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antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
antiatherosclerotic agent
A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent.
anticholesteremic drug
A substance used to lower plasma cholesterol levels.
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View more via ChEBI Ontology
(4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}tetrahydro-2H-pyran-2-one
|
(4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}oxan-2-one
|
IUPAC
|
Antibiotic ML 236A
|
ChEBI
|
compactin diol lactone
|
KEGG COMPOUND
|
compactin diol lactone
|
UniProt
|
desmethylmonacolin J
|
ChEBI
|
ML 236A
|
ChemIDplus
|
ML-236A
|
KEGG COMPOUND
|
58889-19-3
|
CAS Registry Number
|
ChemIDplus
|
1010803
|
PubMed citation
|
Europe PMC
|
12929390
|
PubMed citation
|
Europe PMC
|
15531273
|
PubMed citation
|
Europe PMC
|
16386050
|
PubMed citation
|
Europe PMC
|
2280672
|
PubMed citation
|
Europe PMC
|
2696346
|
PubMed citation
|
Europe PMC
|
28619444
|
PubMed citation
|
Europe PMC
|
3793626
|
PubMed citation
|
Europe PMC
|
6549610
|
PubMed citation
|
Europe PMC
|
908337
|
PubMed citation
|
Europe PMC
|
|