CHEBI:65895 - fattiviracin A1

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ChEBI Name fattiviracin A1
ChEBI ID CHEBI:65895
Definition A carbohydrate-containing antibiotic isolated from the fermentation broth of Streptomyces microflavus strain No. 2445 and exhibits antiviral activity against herpes simplex virus type 1 (HSV-1), varicella-zoster virus (VZV), influenza A virus and human immunodeficiency virus type 1 (HIV-1).
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C81H150O28
Net Charge 0
Average Mass 1572.04090
Monoisotopic Mass 1571.03136
InChI InChI=1S/C81H150O28/c1-54(84)40-32-25-19-13-7-3-4-8-14-20-26-34-42-56(102-78-74(96)70(92)66(88)60(50-82)106-78)43-35-27-21-15-9-5-11-17-23-29-37-46-58-48-64(86)100-52-63-69(91)73(95)77(99)81(109-63)105-59(49-65(87)101-53-62-68(90)72(94)76(98)80(104-58)108-62)47-38-30-24-18-12-6-10-16-22-28-36-44-57(45-39-31-33-41-55(2)85)103-79-75(97)71(93)67(89)61(51-83)107-79/h54-63,66-85,88-99H,3-53H2,1-2H3/t54?,55?,56?,57?,58?,59?,60-,61-,62-,63-,66-,67-,68-,69-,70+,71+,72+,73+,74-,75-,76-,77-,78-,79-,80-,81-/m1/s1
InChIKey YQYKMOMCJFNBBQ-MJSFJGRCSA-N
SMILES CC(O)CCCCCCCCCCCCCCC(CCCCCCCCCCCCCC1CC(=O)OC[C@H]2O[C@@H](OC(CCCCCCCCCCCCCC(CCCCCC(C)O)O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)CC(=O)OC[C@H]3O[C@@H](O1)[C@H](O)[C@@H](O)[C@@H]3O)[C@H](O)[C@@H](O)[C@@H]2O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Metabolite of Species Details
Streptomyces microflavus (NCBI:txid1919) of strain 2445 See: PubMed
Roles Classification
Biological Role(s): anti-HSV-1 agent
An anti-HSV agent agent that destroys or inhibits the replication of herpes simplex virus-1.
anti-HIV-1 agent
An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus.
EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via carbohydrate-containing antibiotic )
Application(s): EC 3.2.1.18 (exo-alpha-sialidase) inhibitor
An antiviral drug targeted at influenza viruses. Its mode of action consists of blocking the function of the viral neuraminidase protein (EC 3.2.1.18), thus preventing the virus from budding from the host cell.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing fattiviracin A1 (CHEBI:65895) has role anti-HIV-1 agent (CHEBI:64947)
fattiviracin A1 (CHEBI:65895) has role anti-HSV-1 agent (CHEBI:64953)
fattiviracin A1 (CHEBI:65895) has role EC 3.2.1.18 (exo-α-sialidase) inhibitor (CHEBI:52425)
fattiviracin A1 (CHEBI:65895) has role metabolite (CHEBI:25212)
fattiviracin A1 (CHEBI:65895) is a β-D-glucoside (CHEBI:22798)
fattiviracin A1 (CHEBI:65895) is a carbohydrate-containing antibiotic (CHEBI:23007)
fattiviracin A1 (CHEBI:65895) is a fatty acid derivative (CHEBI:61697)
fattiviracin A1 (CHEBI:65895) is a macrodiolide (CHEBI:145556)
Registry Numbers Types Sources
214417-77-3 CAS Registry Number ChemIDplus
8186205 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
9820232 PubMed citation Europe PMC
9918397 PubMed citation Europe PMC
Last Modified
02 December 2019